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FXR1 Antibody (711442) in ICC/IF
For immunofluorescence analysis, A375 cells were fixed and permeabilized for detection of endogenous FXR1 using Anti-FXR1 Recombinant Rabbit Superclonal™ Antibody (Product # 711442, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of FXR1 protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938)... View More
Product Details
711442
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rhesus monkey,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Immunogen
Protein corresponding to Human FXR1 (aa 400-600)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2633177
Product Specific Information
This antibody is predicted to react with Monkey, Bovine and Sheep
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
Target Information
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMR1 autosomal homolog 1; fragile X mental retardation autosomal homolog variant p1K; fragile X mental retardation autosomal homolog variant p2K; fragile X mental retardation autosomal homolog variant p4K; fragile X mental retardation autosomal homolog variant p5FK; fragile X mental retardation gene, autosomal homolog; fragile X mental retardation syndrome-related protein 1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation-related protein 1; fragile-X-related protein 1; FXR1P; hFXR1p; mFxr1p; RNA-binding protein FXR1
Gene Aliases: 1110050J02Rik; 9530073J07Rik; AI851072; FXR1; Fxr1h; FXR1P
UniProt ID: (Human) P51114, (Rat) Q5XI81, (Mouse) Q61584
Entrez Gene ID: (Human) 8087, (Rhesus monkey) 710170, (Rat) 361927, (Mouse) 14359
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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