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Abnova
FXYD2 Monoclonal Antibody (1C3-B3)
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Product Details
H00000486-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
1C3-B3
Immunogen
FXYD2 (AAH05302.1, 1 a.a. approximately 64 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MDRWYLGGSP KGDVDPFYYD YETVRNGGLI FAGLAFIVGL LILLSRRFRC GGNKKRRQIN EDEP
Target Information
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXYD domain-containing ion transport regulator 2; Na(+)/K(+) ATPase subunit gamma; regulator 2; Sodium Potassium ATPase; Sodium pump gamma chain; Sodium/potassium-transporting ATPase subunit gamma
Gene Aliases: ATP1C; ATP1G1; FXYD2; HOMG2
UniProt ID: (Human) P54710
Entrez Gene ID: (Human) 486
regulation of cell growth
transport
establishment or maintenance of transmembrane electrochemical gradient
ion transmembrane transport
sodium ion export from cell
regulation of cell proliferation
ATP hydrolysis coupled transmembrane transport
regulation of cardiac conduction
potassium ion import across plasma membrane
regulation of sodium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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