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Invitrogen
FZD3 Polyclonal Antibody
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Product Details
PA5-78242
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human Frizzled 3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.86 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735785
Product Specific Information
Positive Control: Synthetic peptide: 1:8000
Predicted Reactivity: Rat (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; hFz3; mFz3
Gene Aliases: AU020229; D930050A07Rik; Fz-3; Fz3; FZD3
UniProt ID: (Human) Q9NPG1, (Mouse) Q61086
Entrez Gene ID: (Human) 7976, (Mouse) 14365
establishment of planar polarity
neuron migration
neural tube closure
positive regulation of neuroblast proliferation
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
canonical Wnt signaling pathway
sympathetic ganglion development
commissural neuron axon guidance
negative regulation of execution phase of apoptosis
hair follicle development
Wnt signaling pathway, calcium modulating pathway
neuron differentiation
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
Wnt signaling pathway, planar cell polarity pathway
midbrain morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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