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Invitrogen
FZD6 Polyclonal Antibody
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Product Details
PA5-47151
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-6 His19-Val153
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607399
Product Specific Information
In direct ELISAs, approximately 10% cross-reactivity with recombinant human Frizzled-6 is observed, and less than 1% cross-reactivity with recombinant mouse (rm) Frizzled-1, rmFrizzled-2, rmFrizzled-3, rmFrizzled-4, rmFrizzled-7, rmFrizzled-8, and rmFrizzled-9 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 6; Frizzled-6; Frizzled6; Fz-6; FZD-6; mFz6
Gene Aliases: Fz6; Fzd6
UniProt ID: (Mouse) Q61089
Entrez Gene ID: (Mouse) 14368
establishment of planar polarity
neural tube closure
hair follicle development
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
platelet activation
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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