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Invitrogen
FZD6 Polyclonal Antibody
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FIGURE: 1 / 1
FZD6 Antibody (PA5-87953) in WB
Western blot analysis of FZD6 in extracts of various cell line. Samples were incubated with FZD6 Polyclonal antibody (Product # PA5-87953) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-87953
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human FZD6 (NP_0034972)
Conjugate
Form
Liquid
Concentration
2.13 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804535
Product Specific Information
Immunogen sequence: HSLFTCEPIT VPRCMKMAYN MTFFPNLMGH YDQSIAAVEM EHFLPLANLE CSPNIETFLC KAFVPTCIEQ IHVVPPCRKL CEKVYSDCKK LIDTFGIRWP EELECDRLQY CDETVPVTFD PHTEFLGPQK KTEQVQRDIG FWCPRHLKTS GGQGYKFLGI DQCAPPCPNM YFKSDELEFA KSF; Positive Samples: mouse kidney, rat kidney; Cellular Location: Apical cell membrane, Cell membrane, Cell surface, Cytoplasmic vesicle membrane, Membrane, Multi-pass membrane protein
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: frizzled 6; frizzled family receptor 6; Frizzled-6; Frizzled6; Fz-6; FZD-6; mFz6
Gene Aliases: Fz6; Fzd6
UniProt ID: (Mouse) Q61089
Entrez Gene ID: (Mouse) 14368, (Rat) 282581
establishment of planar polarity
neural tube closure
hair follicle development
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
platelet activation
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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