Proteintech

FZR1 Polyclonal Antibody

FZR1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

FZR1 Antibody (16368-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HepG2 cells using 16368-1-AP (FZR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FZR1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16368-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FZR1 Fusion Protein Ag9201 (216-493 aa encoded by BC013413)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: TSQVTRLCD LSVEGDSVTS VGWSERGNLV AVGTHKGFVQ IWDAAAGKKL SMLEGHTARV GALAWNAEQL SSGSRDRMIL QRDIRTPPLQ SERRLQGHRQ EVCGLKWSTD HQLLASGGND NKLLVWNHSS LSPVQQYTEH LAAVKAIAWS PHQHGLLASG GGTADRCIRF WNTLTGQPLQ CIDTGSQVCN LAWSKHANEL VSTHGYSQNQ ILVWKYPSLT QVAKLTGHSY RVLYLAMSPD GEAIVTGAGD ETLRFWNVFS KTRSTKESVS VLNLFTRIR (216-493 aa encoded by BC013413)

Target Information

FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.

Nature communications

Xu X,Chang CW,Li M,Omabe K,Le N,Chen YH,Liang F,Liu Y

Sat Mar 04 00:00:00 UTC 2023

Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma.

Developmental cell

Gong Y,Zou S,Deng D,Wang L,Hu H,Qiu Z,Wei T,Yang P,Zhou J,Zhang Y,Zhu W,Xie X,Liao Z,Yang J,Zhang S,Liu A,Jiang Y,Zou Z,Bai X

Mon Feb 06 00:00:00 UTC 2023

Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma.

Developmental cell

Gong Y,Zou S,Deng D,Wang L,Hu H,Qiu Z,Wei T,Yang P,Zhou J,Zhang Y,Zhu W,Xie X,Liao Z,Yang J,Zhang S,Liu A,Jiang Y,Zou Z,Bai X

Mon Feb 06 00:00:00 UTC 2023

Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis.

Acta pharmacologica Sinica

Yang L,Zheng Y,Miao YM,Yan WX,Geng YZ,Dai Y,Wei ZF

Fri Apr 01 00:00:00 UTC 2022

The cohesin stabilizer Sororin drives G₂-M transition and spindle assembly in mammalian oocytes.

Science advances

Zhou C,Zhang X,Miao Y,Zhang Y,Li Y,Xiong B

Fri Sep 24 00:00:00 UTC 2021

A Cdh1-FoxM1-Apc axis controls muscle development and regeneration.

Cell death & disease

Chen Z,Li L,Xu S,Liu Z,Zhou C,Li Z,Liu Y,Wu W,Huang Y,Kuang M,Fan S,Li H,Li X,Song G,Wu WS,Chen J,Hou Y

Mon Mar 09 00:00:00 UTC 2020

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.

iScience

Valdez-Sinon AN,Lai A,Shi L,Lancaster CL,Gokhale A,Faundez V,Bassell GJ

Fri May 22 00:00:00 UTC 2020

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.

iScience

Valdez-Sinon AN,Lai A,Shi L,Lancaster CL,Gokhale A,Faundez V,Bassell GJ

Fri May 22 00:00:00 UTC 2020

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Molecular and cellular biology

Perry MC,Dufour CR,Eichner LJ,Tsang DW,Deblois G,Muller WJ,Giguère V

Mon Dec 01 00:00:00 UTC 2014

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Molecular and cellular biology

Perry MC,Dufour CR,Eichner LJ,Tsang DW,Deblois G,Muller WJ,Giguère V

Mon Dec 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; Fizzy-related protein homolog; Fzr; hCDH1

View more View less

Gene Aliases: AW108046; CDC20C; CDH1; FYR; FZR; FZR1; FZR2; HCDH; HCDH1; KIAA1242

View more View less

UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5

View more View less

Entrez Gene ID: (Human) 51343, (Mouse) 56371, (Rat) 314642

View more View less

Function(s)

protein binding anaphase-promoting complex binding ubiquitin-protein transferase activator activity

Process(es)

DNA repair mitotic nuclear division positive regulation of cell proliferation anaphase-promoting complex-dependent catabolic process G2 DNA damage checkpoint regulation of meiotic nuclear division protein ubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle lens fiber cell differentiation protein K11-linked ubiquitination negative regulation of cell aging positive regulation of ubiquitin protein ligase activity cellular response to DNA damage stimulus cell cycle

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

FZR1 Polyclonal Antibody

FZR1 Antibody (16368-1-AP) in ICC/IF

Product Details

16368-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!