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Invitrogen
Factor D Polyclonal Antibody
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Factor D Antibody (PA5-79034) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Factor D in paraffin-embedded section of human pancreatic cancer tissue using Factor D Polyclonal Antibody (Product # PA5-79034). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution... View More
Product Details
PA5-79034
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human Factor D recombinant protein (Position: I26-A253).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746150
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human THP-1 whole cell, human Hela whole cell, rat lung tissue, mouse lung tissue, mouse NIH/3T3 whole cell. IHC: human pancreatic cancer tissue, human breast cancer tissue, mouse adipose tissue, rat kidney tissue.
Target Information
Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Complement factor D; complement factor D (adipsin); complement factor D preproprotein; D component (adipsin) of complement; D component of complement (adipsin); EC 3.4.21.46; Endogenous vascular elastase; Properdin factor D
Gene Aliases: ADIPSIN; ADN; CFD; DF; EVE; PFD
UniProt ID: (Human) P00746, (Rat) P32038, (Mouse) P03953
Entrez Gene ID: (Human) 1675, (Rat) 54249, (Mouse) 11537
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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