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Nordic
Factor H Polyclonal Antibody
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Product Details
SHAHU-FH
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Human Factor H
Conjugate
Form
Lyophilized
Purification
IgG Fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Prior to use, an aliquot is thawed slowly at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4 C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the immunoconjugate.
Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
Species Reactivity: The antiserum does not cross-react with any other Human plasma proteins as tested in gel diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
Precipitation assays. In immunoelectrophoresis in agarose-plates use 2 µL human plasma or equivalent against 120 µL antiserum. In double radial immunodiffusion use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL plasma samples (neat and serially diluted) in 2 mm diameter peripheral wells. In electroimmunodiffusion (Laurell) use a concentration of 1% of the antiserum in the gel.
Target Information
Factor H is a serum protein acting as an inhibitor in the complement activation system. I activates the C3/C5 convertase by dissociating its subunits and also acts as a cofactor for the enzyme activity of Factor I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenomedullin binding protein; age-related maculopathy susceptibility 1; beta-1-H-globulin; beta-1H; Complement factor H; complement factor H, isoform b; factor H; factor H-like 1; FHL1 antibody; H factor 1; H factor 1 (complement); H factor 2 (complement); HGNC:4883; MGC88246; RP1-177P10.1
Gene Aliases: AHUS1; AMBP1; ARMD4; ARMS1; CFH; CFHL3; FH; FHL1; HF; HF1; HF2; HUS
UniProt ID: (Human) P08603
Entrez Gene ID: (Human) 3075
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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