Product References
Activated mast cells in skeletal muscle can be a potential mediator for cancer-associated cachexia.
Journal of cachexia, sarcopenia and muscle
Widner DB,Liu C,Zhao Q,Sharp S,Eber MR,Park SH,Files DC,Shiozawa Y
11-5898-82 was used in Flow cytometry/Cell sorting to conclude that activated skeletal muscle-resident mast cells are enriched in cachectic muscles, suggesting skeletal-muscle resident mast cells may serve as a biomarker and mediator for cachexia development to improve patient diagnosis and prognosis.
Sun Aug 01 00:00:00 UTC 2021
NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis.
Frontiers in immunology
Guo X,Xu X,Li T,Yu Q,Wang J,Chen Y,Ding S,Zhu L,Zou G,Zhang X
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Tue Jan 18 00:00:00 UTC 2022
SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis.
The Journal of biological chemistry
Cardenas RA,Gonzalez R,Sanchez E,Ramos MA,Cardenas EI,Rodarte AI,Alcazar-Felix RJ,Isaza A,Burns AR,Heidelberger R,Adachi R
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Mon Aug 02 00:00:00 UTC 2021
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that IgE deficiency reduced atherosclerosis lesion burden, lesion lipid deposition, smooth muscle cell and endothelial cell contents, chemokine MCP (monocyte chemoattractant protein)-1 expression and macrophage accumulation.
Sun Mar 01 00:00:00 UTC 2020
Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li J,Deng Z,Zhang X,Liu F,Yang C,Shi GP
11-5898 was used in Flow cytometry/Cell sorting to support a direct role of IgE in abdominal aortic aneurysm by promoting lesion chemokine expression, inflammatory cell accumulation, MAPK signalling and cytokine expression in mice.
Sat Feb 01 00:00:00 UTC 2020
Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway.
Journal of translational medicine
Yang R,Wang G,Li L,He H,Zheng M,Lu L,Wu S
11-5898 was used in Flow cytometry/Cell sorting to investigate the regulatory effect of Tespa1 on mast cells in the pathogenesis of asthma and its relationship with the interleukin (IL)-4/signal transducers and activators of transcription 6 (STAT6) signaling pathway.
Mon Nov 23 00:00:00 UTC 2020
Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway.
Journal of translational medicine
Yang R,Wang G,Li L,He H,Zheng M,Lu L,Wu S
11-5898 was used in Flow cytometry/Cell sorting to investigate the regulatory effect of Tespa1 on mast cells in the pathogenesis of asthma and its relationship with the interleukin (IL)-4/signal transducers and activators of transcription 6 (STAT6) signaling pathway.
Mon Nov 23 00:00:00 UTC 2020
Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells.
Journal of neuroinflammation
Pérez-Rodríguez MJ,Ibarra-Sánchez A,Román-Figueroa A,Pérez-Severiano F,González-Espinosa C
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Fri Mar 27 00:00:00 UTC 2020
Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models.
Frontiers in genetics
Sun G,Liang X,Qin K,Qin Y,Shi X,Cong P,Mo D,Liu X,Chen Y,He Z
11-5898-82 was used in Flow Cytometry to create two mouse models, KIT D17/+ to mimic the splice mutation, and KIT Dup/+ to partially mimic the duplication mutation of KIT gene in dominant white pigs using CRISPR/Cas9 technology.
Thu Mar 28 00:00:00 UTC 2024
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Fri Jun 19 00:00:00 UTC 2020
Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch.
Immunity
Meixiong J,Anderson M,Limjunyawong N,Sabbagh MF,Hu E,Mack MR,Oetjen LK,Wang F,Kim BS,Dong X
11-5898 was used in Flow cytometry/Cell sorting to explore how mast-cell-expressed Mas-related G-protein coupled receptors cause non-histaminergic itching in mice.
Tue May 21 00:00:00 UTC 2019
Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.
PLoS biology
Kobayashi T,Shimabukuro-Demoto S,Tsutsui H,Toyama-Sorimachi N
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Fri Nov 01 00:00:00 UTC 2019
Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.
Nature communications
Liu CL,Zhang X,Liu J,Wang Y,Sukhova GK,Wojtkiewicz GR,Liu T,Tang R,Achilefu S,Nahrendorf M,Libby P,Guo J,Zhang JY,Shi GP
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Western Blot
Wed Sep 04 00:00:00 UTC 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 UTC 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 UTC 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 UTC 2019
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.
Cell death & disease
Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J
Tue Mar 06 00:00:00 UTC 2018
MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity.
Frontiers in immunology
Knolle MD,Chin SB,Rana BMJ,Englezakis A,Nakagawa R,Fallon PG,Git A,McKenzie ANJ
11-5898 was used in Flow cytometry/Cell sorting to identify a subset of micro-RNAs that are regulated upon group-2 innate lymphoid cells (ILC2) activation, and establish a specific role for miR-155 in regulating ILC2 survival following activation.
Mon Sep 30 00:00:00 UTC 2019
IL-33/ST2 signalling and crosstalk with FcεRI and TLR4 is targeted by the parasitic worm product, ES-62.
Scientific reports
Ball DH,Al-Riyami L,Harnett W,Harnett MM
11-5898 was used in Flow cytometry/Cell sorting to investigate whether ES62 targets the MyD88-IL-33 signalling network by subverting ST2-signalling to exhibit therapeutic potential in allergy.
Wed Mar 14 00:00:00 UTC 2018
Stimulus strength determines the BTK-dependence of the SHIP1-deficient phenotype in IgE/antigen-triggered mast cells.
Scientific reports
Zorn CN,Simonowski A,Huber M
Fri Oct 19 00:00:00 UTC 2018
Transcriptional Heterogeneity of Mast Cells and Basophils upon Activation.
Journal of immunology (Baltimore, Md. : 1950)
Chhiba KD,Hsu CL,Berdnikovs S,Bryce PJ
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that mast cells and basophils have cell- and activation-specific transcriptional responses and suggest that context specific gene networks and pathways may shape how the immune system responds to allergens and innate cytokines.
Thu Jun 15 00:00:00 UTC 2017
Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency.
Scientific reports
Poplutz M,Levikova M,Lüscher-Firzlaff J,Lesina M,Algül H,Lüscher B,Huber M
11-5898 was used in in vitro experiments to describe induction of endotoxin tolerance by rough lipopolysaccharide in murine bone marrow-derived and peritoneal mast cells.
Mon Jul 03 00:00:00 UTC 2017
Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.
Scientific reports
Nakamura Y,Ishimaru K,Shibata S,Nakao A
11589882 was used in flow cytometry to report how steady-state plasma histamine levels are regulated and affected by environmental factors
Wed Jan 11 00:00:00 UTC 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
11-5898-82 was used in Flow Cytometry to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Thu Mar 14 00:00:00 UTC 2024
Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
The Journal of experimental medicine
Henry EK,Sy CB,Inclan-Rico JM,Espinosa V,Ghanny SS,Dwyer DF,Soteropoulos P,Rivera A,Siracusa MC
11589882 was used in flow cytometry to find a role for Car enzymes in regulating mast cell lineage commitment
Mon Aug 22 00:00:00 UTC 2016
Innate lymphoid cells contribute to allergic airway disease exacerbation by obesity.
The Journal of allergy and clinical immunology
Everaere L,Ait-Yahia S,Molendi-Coste O,Vorng H,Quemener S,LeVu P,Fleury S,Bouchaert E,Fan Y,Duez C,de Nadai P,Staels B,Dombrowicz D,Tsicopoulos A
11-5898 was used in Flow cytometry/Cell sorting to indicate that high-fat diet-induced obesity might exacerbate allergic airway inflammation through mechanisms involving ILC2s and ILC3s.
Tue Nov 01 00:00:00 UTC 2016
Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life.
Mucosal immunology
Patel KR,Aven L,Shao F,Krishnamoorthy N,Duvall MG,Levy BD,Ai X
11-5898 was used in Flow cytometry/Cell sorting to identify a essential role of mast cells in mediating airway smooth muscle hyperinnervation following early-life insults by producing neurotrophin 4.
Tue Nov 01 00:00:00 UTC 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC (ILC2) response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 UTC 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
11-5898 was used in Flow cytometry/Cell sorting to gain a better understanding of FcεRI-mediated mast cell degranulation and to identify genes involved in mast cell activation via RNAi screening.
Sun May 01 00:00:00 UTC 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
11-5898 was used in Flow cytometry/Cell sorting to gain a better understanding of FcεRI-mediated mast cell degranulation and to identify genes involved in mast cell activation via RNAi screening.
Sun May 01 00:00:00 UTC 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
11-5898 was used in Flow cytometry/Cell sorting to gain a better understanding of FcεRI-mediated mast cell degranulation and to identify genes involved in mast cell activation via RNAi screening.
Sun May 01 00:00:00 UTC 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
11-5898 was used in Flow cytometry/Cell sorting to gain a better understanding of FcεRI-mediated mast cell degranulation and to identify genes involved in mast cell activation via RNAi screening.
Sun May 01 00:00:00 UTC 2016
Wnt-β-Catenin Signaling Promotes the Maturation of Mast Cells.
BioMed research international
Yamaguchi T,Nishijima M,Tashiro K,Kawabata K
11-5898 was used in Flow cytometry/Cell sorting to show that Wnt5a could promote the maturation of mast cells via the canonical Wnt signaling pathway.
Thu Jan 19 00:00:00 UTC 2017
Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice.
PloS one
Meurer SK,Neß M,Weiskirchen S,Kim P,Tag CG,Kauffmann M,Huber M,Weiskirchen R
Mon Jul 24 00:00:00 UTC 2017
iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following γPGA Stimulation.
PloS one
Park HJ,Lee SW,Park SH,Hong S
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that γPGA-induced iNKT cell polarization toward the Th1 phenotype induces apoptotic basophil depletion, leading to the suppression of Th2 immune responses.
Mon Aug 22 00:00:00 UTC 2016
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
Nature
Brestoff JR,Kim BS,Saenz SA,Stine RR,Monticelli LA,Sonnenberg GF,Thome JJ,Farber DL,Lutfy K,Seale P,Artis D
11-5898 was used in Flow cytometry/Cell sorting to study how ILC2s can regulate adipose function and metabolic homeostasis.
Thu Mar 12 00:00:00 UTC 2015
Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.
Endocrinology
Lee YJ,Liu C,Liao M,Sukhova GK,Shirakawa J,Abdennour M,Iamarene K,Andre S,Inouye K,Clement K,Kulkarni RN,Banks AS,Libby P,Shi GP
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Western Blot
Sun Nov 01 00:00:00 UTC 2015
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.
Oncotarget
Drube S,Weber F,Loschinski R,Beyer M,Rothe M,Rabenhorst A,Göpfert C,Meininger I,Diamanti MA,Stegner D,Häfner N,Böttcher M,Reinecke K,Herdegen T,Greten FR,Nieswandt B,Hartmann K,Krämer OH,Kamradt T
11-5898 was used in Flow cytometry/Cell sorting to conclude that subthreshold IKK activation is crucial to mediate the full IL-33-induced effector functions in primary mast cells and to mediate uncontrolled proliferation of neoplastic mast cells.
Tue Mar 10 00:00:00 UTC 2015
Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages.
PloS one
Lee SW,Park HJ,Jeon SH,Lee C,Seong RH,Park SH,Hong S
11-5898 was used in Flow cytometry/Cell sorting to investigate the role of a SWI3-related gene in experimental autoimmune encephalomyelitis development.
Mon Apr 11 00:00:00 UTC 2016
Tie2 Signaling Enhances Mast Cell Progenitor Adhesion to Vascular Cell Adhesion Molecule-1 (VCAM-1) through α4β1 Integrin.
PloS one
Kanemaru K,Noguchi E,Tokunaga T,Nagai K,Hiroyama T,Nakamura Y,Tahara-Hanaoka S,Shibuya A
11-5898 was used in Flow cytometry/Cell sorting to suggest that Tie2 signaling induces α4β1 integrin activation on BM-MCps for adhesion to VCAM-1.
Sun Jun 26 00:00:00 UTC 2016
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Nature medicine
Schönhuber N,Seidler B,Schuck K,Veltkamp C,Schachtler C,Zukowska M,Eser S,Feyerabend TB,Paul MC,Eser P,Klein S,Lowy AM,Banerjee R,Yang F,Lee CL,Moding EJ,Kirsch DG,Scheideler A,Alessi DR,Varela I,Bradley A,Kind A,Schnieke AE,Rodewald HR,Rad R,Schmid RM,Schneider G,Saur D
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Immunofluorescence
Sat Nov 01 00:00:00 UTC 2014
Circadian regulation of allergic reactions by the mast cell clock in mice.
The Journal of allergy and clinical immunology
Nakamura Y,Nakano N,Ishimaru K,Hara M,Ikegami T,Tahara Y,Katoh R,Ogawa H,Okumura K,Shibata S,Nishiyama C,Nakao A
11-5898 was used in Flow cytometry/Cell sorting to study the circadian regulation of allergic reactions by the mast cell clock in mice.
Sat Feb 01 00:00:00 UTC 2014
Does β-hexosaminidase function only as a degranulation indicator in mast cells? The primary role of β-hexosaminidase in mast cell granules.
Journal of immunology (Baltimore, Md. : 1950)
Fukuishi N,Murakami S,Ohno A,Yamanaka N,Matsui N,Fukutsuji K,Yamada S,Itoh K,Akagi M
11-5898 was used in Flow cytometry/Cell sorting to investigate the biological role of Β-hexosaminidase in mast cell granules.
Fri Aug 15 00:00:00 UTC 2014
Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations.
Journal of lipid research
Lundström SL,Saluja R,Adner M,Haeggström JZ,Nilsson G,Wheelock CE
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that CTLMCs and MLMCs secrete differing oxylipin profiles at baseline and following calcium ionophore stimulation.
Tue Jan 01 00:00:00 UTC 2013
Sequential engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic Rhinitis.
Journal of immunology (Baltimore, Md. : 1950)
Shiraishi Y,Jia Y,Domenico J,Joetham A,Karasuyama H,Takeda K,Gelfand EW
11-5898 was used in Flow cytometry/Cell sorting to demonstrate how the development of allergic rhinitis has two distinct stages: histamine release from FcεRI-activated mast cells, followed by histamine-mediated recruitment of H(4)R-expressing basophils to the nasal cavity.
Tue Jan 15 00:00:00 UTC 2013
Fasciola hepatica tegumental coat impairs mast cells' ability to drive Th1 immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Vukman KV,Adams PN,Metz M,Maurer M,O'Neill SM
11-5898 was used in Flow cytometry/Cell sorting to investigate the mechanism by which Fasciola hepatica impairs mast cells' ability to induce Th1 immune responses.
Fri Mar 15 00:00:00 UTC 2013
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Suzukawa M,Miller M,Rosenthal P,Cho JY,Doherty TA,Varki A,Broide D
11-5898 was used in Flow cytometry/Cell sorting to study the regulated murine expression of Siglec-F ligand in immune and lung airway epithelial cells.
Sat Jun 15 00:00:00 UTC 2013
LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP.
Cellular signalling
Hochdörfer T,Tiedje C,Stumpo DJ,Blackshear PJ,Gaestel M,Huber M
11-5898 was used in in vitro experiments to suggest that control of cytokine mRNA stability and translation in mast cells is exerted by proteins different from p38-MK2-tristetraprolin (TTP).
Sat Jun 01 00:00:00 UTC 2013
Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Blood
Carbonneau CL,Despars G,Rojas-Sutterlin S,Fortin A,Le O,Hoang T,Beauséjour CM
11-5898 was used in Flow cytometry/Cell sorting to investigate the effect of ionizing radiation on murine bone marrow-derived stromal cell populations, and overall bone marrow homeostasis.
Thu Jan 19 00:00:00 UTC 2012
Antibodies and IL-3 support helminth-induced basophil expansion.
Proceedings of the National Academy of Sciences of the United States of America
Herbst T,Esser J,Prati M,Kulagin M,Stettler R,Zaiss MM,Hewitson JP,Merky P,Verbeek JS,Bourquin C,Camberis M,Prout M,Maizels RM,Le Gros G,Harris NL
11-5898 was used in Flow cytometry/Cell sorting to study the support of helminth-induced basophil expansion.
Tue Sep 11 00:00:00 UTC 2012
The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.
The American journal of pathology
Piliponsky AM,Chen CC,Rios EJ,Treuting PM,Lahiri A,Abrink M,Pejler G,Tsai M,Galli SJ
11-5898 was used in Flow cytometry/Cell sorting to investigate the role of chymase mouse mast cell protease 4 in a mouse model of sepsis.
Sat Sep 01 00:00:00 UTC 2012
Comparison of bone marrow-derived and mucosal mast cells in controlling intramacrophage Francisella tularensis replication.
Experimental biology and medicine (Maywood, N.J.)
Hunter C,Rodriguez A,Yu JJ,Chambers J,Guentzel MN,Arulanandam B
11-5898 was used in Flow cytometry/Cell sorting to investigate the role of mucousal mast cells in controlling the intracellular replication of bacterial pathogen F. tularensis in macrophages.
Fri Jun 01 00:00:00 UTC 2012
FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatment.
PloS one
Saluja R,Delin I,Nilsson GP,Adner M
11-5898 was used in Flow cytometry/Cell sorting to suggest that infections might exaggerate the severity of allergic reactions by enhancing mediator release from mast cells.
Wed Jan 16 00:00:00 UTC 2013
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice.
The Journal of allergy and clinical immunology
Arias K,Chu DK,Flader K,Botelho F,Walker T,Arias N,Humbles AA,Coyle AJ,Oettgen HC,Chang HD,Van Rooijen N,Waserman S,Jordana M
11-5898 was used in Flow cytometry/Cell sorting to investigate the relative contribution of immunoglobulin-dependent effector pathways to anaphylactic responses to food.
Wed Jun 01 00:00:00 UTC 2011
Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.
The Journal of allergy and clinical immunology
Nakamura Y,Harama D,Shimokawa N,Hara M,Suzuki R,Tahara Y,Ishimaru K,Katoh R,Okumura K,Ogawa H,Shibata S,Nakao A
11-5898 was used in Flow cytometry/Cell sorting to show that Per2 regulates a time-of-day-dependent variation in a passive cutaneous anaphylactic reaction in mice.
Fri Apr 01 00:00:00 UTC 2011
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice.
Laboratory investigation; a journal of technical methods and pathology
Piconese S,Costanza M,Musio S,Tripodo C,Poliani PL,Gri G,Burocchi A,Pittoni P,Gorzanelli A,Colombo MP,Pedotti R
11-5898 was used in Flow cytometry/Cell sorting to investigate the potential detrimental role of mast cells in experimental autoimmune encephalomyelitis.
Fri Apr 01 00:00:00 UTC 2011
Inhibitory effect of hot-water extract of quince (Cydonia oblonga) on immunoglobulin E-dependent late-phase immune reactions of mast cells.
Cytotechnology
Kawahara T,Iizuka T
11-5898 was used in Flow cytometry/Cell sorting to suggest that a crude hot-water extract of quince inhibits mast cell function during type 1 allergic reactions by suppressing inflammatory cytokine expression and lipid mediator production.
Tue Mar 01 00:00:00 UTC 2011
Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells.
The Journal of biological chemistry
Nakano N,Nishiyama C,Yagita H,Koyanagi A,Ogawa H,Okumura K
11-5898 was used in Flow cytometry/Cell sorting to show that activation of class II transactivator pIII plays an important role in MHC class II expression in mast cells.
Fri Apr 08 00:00:00 UTC 2011
Aberrant immune responses in a mouse with behavioral disorders.
PloS one
Heo Y,Zhang Y,Gao D,Miller VM,Lawrence DA
11-5898 was used in Flow cytometry/Cell sorting to study the role of the immune system in a mouse model with autistic-like behaviour, showing that these mice have higher amounts of serum IgG and IgE, and elevated expression of cytokines in the brain.
Tue Dec 06 00:00:00 UTC 2011
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.
The American journal of pathology
Piliponsky AM,Chen CC,Grimbaldeston MA,Burns-Guydish SM,Hardy J,Kalesnikoff J,Contag CH,Tsai M,Galli SJ
11-5898 was used in Flow cytometry/Cell sorting to investigate the roles of mast cells and their derived proteins in two models of severe bacterial infection.
Mon Feb 01 00:00:00 UTC 2010
Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis.
Cell death & disease
Karlberg M,Ekoff M,Labi V,Strasser A,Huang D,Nilsson G
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that Bax has a predominant and Bak a minor role in cytokine deprivation-induced apoptosis in mast cells.
Thu May 13 00:00:00 UTC 2010
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.
Nature immunology
Perrigoue JG,Saenz SA,Siracusa MC,Allenspach EJ,Taylor BC,Giacomin PR,Nair MG,Du Y,Zaph C,van Rooijen N,Comeau MR,Pearce EJ,Laufer TM,Artis D
Wed Jul 01 00:00:00 UTC 2009
Cell-cell cooperation at the T helper cell/mast cell immunological synapse.
Blood
Gaudenzio N,Espagnolle N,Mars LT,Liblau R,Valitutti S,Espinosa E
11-5898 was used in Flow cytometry/Cell sorting to investigate whether cognate interactions between mast cells and class II-restricted CD4(+) T cells occur.
Thu Dec 03 00:00:00 UTC 2009
Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation.
Blood
Piconese S,Gri G,Tripodo C,Musio S,Gorzanelli A,Frossi B,Pedotti R,Pucillo CE,Colombo MP
11-5898 was used in Flow cytometry/Cell sorting to show that mast cells, an early source of inflammatory mediators, are able to counteract Treg inhibition over effector T cells.
Thu Sep 24 00:00:00 UTC 2009
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.
The Journal of clinical investigation
Jin H,Oyoshi MK,Le Y,Bianchi T,Koduru S,Mathias CB,Kumar L,Le Bras S,Young D,Collins M,Grusby MJ,Wenzel J,Bieber T,Boes M,Silberstein LE,Oettgen HC,Geha RS
Published figure using FceR1 alpha monoclonal antibody (Product # 11-5898-82) in Flow Cytometry
Thu Jan 01 00:00:00 UTC 2009
Notch signaling confers antigen-presenting cell functions on mast cells.
The Journal of allergy and clinical immunology
Nakano N,Nishiyama C,Yagita H,Koyanagi A,Akiba H,Chiba S,Ogawa H,Okumura K
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that Dll1/Notch signaling confers the functions of an antigen-presenting cell on mast cells, which induce TH2 differentiation.
Thu Jan 01 00:00:00 UTC 2009
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.
Journal of immunology (Baltimore, Md. : 1950)
McKee AS,Munks MW,MacLeod MK,Fleenor CJ,Van Rooijen N,Kappler JW,Marrack P
11-5898 was used in Flow cytometry/Cell sorting to investigate how the body recognises alum, showing that it induces innate immune responses through macrophage and mast cell sensors.
Thu Oct 01 00:00:00 UTC 2009
CD200R surface expression as a marker of murine basophil activation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Torrero MN,Larson D,Hübner MP,Mitre E
11-5898 was used in Flow cytometry/Cell sorting to develop an assay that measures murine basophil activation by utilizing CD200R as an activation marker.
Sun Mar 01 00:00:00 UTC 2009
The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.
Blood
Ghinassi B,Sanchez M,Martelli F,Amabile G,Vannucchi AM,Migliaccio G,Orkin SH,Migliaccio AR
11-5898 was used in Flow cytometry/Cell sorting to confirm the crucial role played by Gata1 in haematopoietic commitment and to identify a new target for Gata1 action.
Thu Feb 15 00:00:00 UTC 2007
Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections.
Blood
Nakano N,Nishiyama C,Kanada S,Niwa Y,Shimokawa N,Ushio H,Nishiyama M,Okumura K,Ogawa H
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that mast cells are a crucial source of functional IL-12.
Fri Jun 01 00:00:00 UTC 2007
IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals.
Journal of leukocyte biology
Ho LH,Ohno T,Oboki K,Kajiwara N,Suto H,Iikura M,Okayama Y,Akira S,Saito H,Galli SJ,Nakae S
11-5898 was used in Flow cytometry/Cell sorting to reveal potential roles for IL-33 in mast cell- and Th2 cytokine-associated immune responses and disorders.
Sat Dec 01 00:00:00 UTC 2007
A new approach for analyzing cellular infiltration during allergic airway inflammation.
Journal of immunological methods
Hoffmann PR,Gurary A,Hoffmann FW,Jourdan-Le Saux C,Teeters K,Hashimoto AC,Tam EK,Berry MJ
11-5898 was used in Flow cytometry/Cell sorting to investigate a new approach for analyzing cellular infiltration during allergic airway inflammation.
Sat Dec 01 00:00:00 UTC 2007
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion.
The Journal of experimental medicine
Fallon PG,Ballantyne SJ,Mangan NE,Barlow JL,Dasvarma A,Hewett DR,McIlgorm A,Jolin HE,McKenzie AN
11-5898 was used in Flow cytometry/Cell sorting to demonstrate that IL-25-regulated cells appear in the draining lymph nodes, providing a type 2 cytokine source during initiation of worm expulsion.
Mon Apr 17 00:00:00 UTC 2006
Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation.
Cell death and differentiation
Alfredsson J,Puthalakath H,Martin H,Strasser A,Nilsson G
11-5898 was used in Flow cytometry/Cell sorting to suggest that Bim and possibly also other BH3-only proteins control growth factor withdrawal-induced mast cell apoptosis.
Tue Feb 01 00:00:00 UTC 2005
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite.
The Journal of experimental medicine
Min B,Prout M,Hu-Li J,Zhu J,Jankovic D,Morgan ES,Urban JF,Dvorak AM,Finkelman FD,LeGros G,Paul WE
11-5898 was used in Flow cytometry/Cell sorting to examine the production of interleukin-4 during infection by the intestinal nematode Nippostrongylus brasiliensis using green fluorescent protein-expressing mice.
Mon Aug 16 00:00:00 UTC 2004
