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          • Primary Antibodies ›
          • Ferritin Heavy Chain Antibodies

          Invitrogen

          Ferritin Heavy Chain Polyclonal Antibody

          Advanced Verification
          2 Published Figures
          2 References
          View all (24) Ferritin Heavy Chain antibodies

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          Datasheet
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          Datasheet
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          Cite Ferritin Heavy Chain Polyclonal Antibody

          • Antibody Testing Data (5)
          • Published Figures (2)
          • Advanced Verification (1)
          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
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          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          Ferritin Heavy Chain Antibody (PA5-19058) in ICC/IF

          Immunofluorescence analysis of Ferritin Heavy Chain was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ferritin Heavy Chain Polyclonal Antibody (Product # PA5-19058) at 1:100 dilution in 0.1% BSA, incubate... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          Ferritin Heavy Chain Antibody in Immunocytochemistry (ICC/IF)
          Ferritin Heavy Chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody in Western Blot (WB)
          Ferritin Heavy Chain Antibody

          Product Details

          PA5-19058

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-3 µg/mL
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          2-4 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          1:100
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (DKHTLGDSDNES) corresponding to the C-terminus amino acids of FTH1 (aa 172-183).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11009180

          Product Specific Information

          This antibody is predicted to react with canine based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

          Target Information

          FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; ferritin, heavy polypeptide 1; frih; MGC104426; placenta immunoregulatory factor; proliferation-inducing protein 15

          View more View less

          Gene Aliases: FHC; FTH; FTH1; FTHL6; HFE5; OK/SW-cl.84; PIG15; PLIF

          View more View less

          UniProt ID: (Human) P02794

          View more View less

          Entrez Gene ID: (Human) 2495

          View more View less

          Function(s)
          ferroxidase activity iron ion binding protein binding ferric iron binding
          Process(es)
          iron ion transport cellular iron ion homeostasis intracellular sequestering of iron ion immune response negative regulation of cell proliferation negative regulation of fibroblast proliferation oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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