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Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ferritin L subunit; Ferritin L subunit 1; ferritin L-chain; Ferritin light chain; Ferritin light chain 1; ferritin light polypeptide-like 3; ferritin, light polypeptide; fril
Gene Aliases: FTL; Ftl-1; Ftl1; L-ferritin; LFTD; NBIA3
UniProt ID: (Human) P02792, (Rat) P02793
Entrez Gene ID: (Human) 2512, (Mouse) 14325, (Rat) 29292
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