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Invitrogen
Ferroportin Polyclonal Antibody
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Ferroportin Antibody (PA5-115915) in IHC (P)
Immunohistochemistry analysis of Ferroportin in human colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115915) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115915
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC40A1(Accession Q9NP59), corresponding to amino acid residues G12-A62.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900549
Product Specific Information
Antibody detects endogenous levels of total SLC40A1.
Target Information
SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1
Gene Aliases: Dusg; FPN; FPN1; Fpt1; HFE4; IREG1; MST079; MSTP079; MTP; MTP1; Ol5; Pcm; SLC11A3; Slc39a1; SLC40A1
UniProt ID: (Human) Q9NP59, (Mouse) Q9JHI9, (Rat) Q923U9
Entrez Gene ID: (Human) 30061, (Mouse) 53945, (Rat) 170840
lymphocyte homeostasis
endothelium development
cellular iron ion homeostasis
regulation of transcription from RNA polymerase II promoter in response to iron
iron ion transmembrane transport
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
spleen trabecula formation
multicellular organismal iron ion homeostasis
ferrous iron export
transport
ion transport
iron ion transport
spleen development
iron ion homeostasis
ferrous iron transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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