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Fibrinogen alpha chain Polyclonal Antibody

Fibrinogen alpha chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 3

Fibrinogen alpha chain Antibody (20645-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver tissue slide using 20645-1-AP (Fibrinogen alpha chain antibody) at dilution of 1:200 (under 40x lens).

Fibrinogen alpha chain Antibody in Western Blot (WB)

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Product Details

20645-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Fibrinogen alpha chain Fusion Protein Ag9567 (20-218 aa encoded by BC020764)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: ADSGEGDFL AEGGGVRGPR VVERHQSACK DSDWPFCSGE DWNYKCPSGC RMKGLIDEVN QDFTNRINKL KNSLFEYQKN NKDSHSLTTN IMEILRGDFS SANNRDNTYN RVSEDLRSRI EVLKRKVIEK VTANNLLVAR VTTEETPHLK ARAIKWQMRP EVKPIMKEHI APREAMLNLA LSEVSTLLLW GSLPCPPRLS (20-218 aa encoded by BC020764)

Target Information

Fibrinogen is a soluble protein found in blood plasma and is produced by the liver cells. The protein is a hexamer consisting of two sets of disulfide linked chains. Fibrinogen is essential for blood coagulation as the precursor of fibrin. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Geniposide alleviates VEGF-induced angiogenesis by inhibiting VEGFR2/PKC/ERK1/2-mediated SphK1 translocation.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Wang Y,Wu H,Gui BJ,Liu J,Rong GX,Deng R,Bu YH,Zhang H

Wed Jun 01 00:00:00 UTC 2022

Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies.

Nature communications

Zheng DW,Hong S,Zhang QL,Dong X,Pan P,Song WF,Song W,Cheng SX,Zhang XZ

Wed Sep 30 00:00:00 UTC 2020

Serum proteomic predicts effectiveness and reveals potential biomarkers for complications in liver transplant patients.

Aging

Wang W,Wang B,Liu C,Yan J,Xiong X,Wang X,Yang J,Guo B,Huang C

Fri Jun 12 00:00:00 UTC 2020

Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase.

Journal of thrombosis and haemostasis : JTH

Poole LG,Pant A,Baker KS,Kopec AK,Cline-Fedewa HM,Iismaa SE,Flick MJ,Luyendyk JP

Tue Jan 01 00:00:00 UTC 2019

Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase.

Journal of thrombosis and haemostasis : JTH

Poole LG,Pant A,Baker KS,Kopec AK,Cline-Fedewa HM,Iismaa SE,Flick MJ,Luyendyk JP

Tue Jan 01 00:00:00 UTC 2019

Fibrinogen Chains Intrinsic to the Brain.

Frontiers in neuroscience

Golanov EV,Sharpe MA,Regnier-Golanov AS,Del Zoppo GJ,Baskin DS,Britz GW

Thu Oct 01 00:00:00 UTC 2020

Fibrinogen Chains Intrinsic to the Brain.

Frontiers in neuroscience

Golanov EV,Sharpe MA,Regnier-Golanov AS,Del Zoppo GJ,Baskin DS,Britz GW

Thu Oct 01 00:00:00 UTC 2020

Fibrinogen Chains Intrinsic to the Brain.

Frontiers in neuroscience

Golanov EV,Sharpe MA,Regnier-Golanov AS,Del Zoppo GJ,Baskin DS,Britz GW

Thu Oct 01 00:00:00 UTC 2020

SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.

Free radical biology & medicine

Ma Y,Qi Y,Wang L,Zheng Z,Zhang Y,Zheng J

Mon Apr 01 00:00:00 UTC 2019

SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.

Free radical biology & medicine

Ma Y,Qi Y,Wang L,Zheng Z,Zhang Y,Zheng J

Mon Apr 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen α chain; fibrinogen, A alpha polypeptide; Fibrinogenα chain

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Gene Aliases: ENSMUSG00000059807; FGA; Fib; Fib2

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UniProt ID: (Human) P02671, (Mouse) E9PV24

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Entrez Gene ID: (Human) 2243, (Mouse) 14161

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Function(s)

receptor binding structural molecule activity protein binding protein binding, bridging metal ion binding cell adhesion molecule binding

Process(es)

adaptive immune response platelet degranulation protein complex assembly acute-phase response cell-matrix adhesion signal transduction blood coagulation extracellular matrix organization plasminogen activation response to estradiol response to genistein positive regulation of heterotypic cell-cell adhesion fibrinolysis induction of bacterial agglutination response to morphine cellular protein complex assembly cellular protein metabolic process innate immune response positive regulation of vasoconstriction positive regulation of exocytosis response to cycloheximide positive regulation of protein secretion protein polymerization response to calcium ion positive regulation of ERK1 and ERK2 cascade platelet aggregation cellular response to interleukin-6 cellular response to organic cyclic compound blood coagulation, common pathway blood coagulation, fibrin clot formation positive regulation of peptide hormone secretion liver regeneration positive regulation of substrate adhesion-dependent cell spreading negative regulation of extrinsic apoptotic signaling pathway via death domain receptors cellular response to granulocyte colony-stimulating factor negative regulation of endothelial cell apoptotic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Fibrinogen alpha chain Polyclonal Antibody

Fibrinogen alpha chain Antibody (20645-1-AP) in IHC (P)

Product Details

20645-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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