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Invitrogen
Fibrinogen alpha chain Recombinant Rabbit Monoclonal Antibody (7K8J1)
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FIGURE: 1 / 4
Fibrinogen alpha chain Antibody (MA5-37943) in IHC (P)
Immunohistochemistry analysis of Fibrinogen alpha chain in paraffin-embedded human placenta. Samples were incubated with Fibrinogen alpha chain Monoclonal antibody (Product # MA5-37943) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-37943
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7K8J1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Fibrinogen alpha chain (FGA) (FGA) (P02671)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897863
Product Specific Information
Positive Samples: Human plasma, Rat liver
Immunogen sequence: NDEGEGEFWL GNDYLHLLTQ RGSVLRVELE DWAGNEAYAE YHFRVGSEAE GYALQVSSYE GTAGDALIEG SVEEGAEYTS HNNMQFSTFD RDADQWEENC A
Target Information
Fibrinogen is a soluble protein found in blood plasma and is produced by the liver cells. The protein is a hexamer consisting of two sets of disulfide linked chains. Fibrinogen is essential for blood coagulation as the precursor of fibrin. It is converted to fibrin by the action of thrombin in the presence of calcium ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen α chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; Fibrinogenα chain
Gene Aliases: Ac1873; ENSMUSG00000059807; Fba5e; FGA; Fib; Fib2
UniProt ID: (Human) P02671, (Mouse) E9PV24
Entrez Gene ID: (Human) 2243, (Mouse) 14161, (Rat) 361969
adaptive immune response
platelet degranulation
protein complex assembly
acute-phase response
cell-matrix adhesion
signal transduction
blood coagulation
extracellular matrix organization
plasminogen activation
response to estradiol
response to genistein
positive regulation of heterotypic cell-cell adhesion
fibrinolysis
induction of bacterial agglutination
response to morphine
cellular protein complex assembly
cellular protein metabolic process
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
response to cycloheximide
positive regulation of protein secretion
protein polymerization
response to calcium ion
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to interleukin-6
cellular response to organic cyclic compound
blood coagulation, common pathway
blood coagulation, fibrin clot formation
positive regulation of peptide hormone secretion
liver regeneration
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cellular response to granulocyte colony-stimulating factor
negative regulation of endothelial cell apoptotic process
platelet activation
cellular response to cytokine stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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