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Invitrogen
Fibrinogen alpha chain Monoclonal Antibody (KT9)
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Fibrinogen alpha chain Antibody (MA5-49571) in IHC (P)
Immunohistochemistry analysis of Fibrinogen alpha chain in formalin-fixed paraffin-embedded human placenta tissue. Samples were incubated in Fibrinogen alpha chain monoclonal antibody (Product # MA5-49571) using a dilution of 2 µg/mL at room temperature for 1 hour followed by poly-peroxidase conjugated goat anti-mouse lgG (which cross reacts with rat lgG) secondary antibody. Antigen was retrieved thorough a... View More
Product Details
MA5-49571
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
KT9
Immunogen
Fibrinogen purified from human blood containing α,β and γ chains
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3090640
Product Specific Information
This product was used in both Indirect and Sandwich ELISA.
Target Information
Fibrinogen is a soluble protein found in blood plasma and is produced by the liver cells. The protein is a hexamer consisting of two sets of disulfide linked chains. Fibrinogen is essential for blood coagulation as the precursor of fibrin. It is converted to fibrin by the action of thrombin in the presence of calcium ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen α chain; fibrinogen, A alpha polypeptide; Fibrinogenα chain
Gene Aliases: FGA; Fib2
UniProt ID: (Human) P02671
Entrez Gene ID: (Human) 2243
adaptive immune response
platelet degranulation
protein complex assembly
acute-phase response
cell-matrix adhesion
signal transduction
blood coagulation
extracellular matrix organization
plasminogen activation
response to estradiol
response to genistein
positive regulation of heterotypic cell-cell adhesion
fibrinolysis
induction of bacterial agglutination
response to morphine
cellular protein complex assembly
cellular protein metabolic process
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
response to cycloheximide
positive regulation of protein secretion
protein polymerization
response to calcium ion
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
cellular response to interleukin-6
cellular response to organic cyclic compound
blood coagulation, common pathway
blood coagulation, fibrin clot formation
positive regulation of peptide hormone secretion
liver regeneration
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
cellular response to granulocyte colony-stimulating factor
negative regulation of endothelial cell apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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