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Invitrogen
Filamin 2 Polyclonal Antibody
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Product Details
PA5-88919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_0014493)
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805220
Product Specific Information
Immunogen sequence: IPGNWFQMVS AQERLTRTFT RSSHTYTRTE RTEISKTRGG ETKREVRVEE STQVGGDPFP AVFGDFLGRE RLGSFGSITR QQEGEASSQD MTAQVTSPSG KVEAAEIVEG EDSAYSVRFV PQEMGPHTVA VKYRGQHVPG SPFQFTVGPL GEGGAHKVRA GGTGLERGVA GVPAEFSIWT R; Positive Samples: A-549, LO2, NIH/3T3; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein, Z line, cytoskeleton, myofibril, sarcomere
Target Information
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABP-280-like protein; ABP-L; ABP-L, gamma filamin; actin binding protein 280; actin-binding protein 280; Actin-binding-like protein; Filamin C gamma; filamin C, gamma; filamin, gamma; Filamin-2; Filamin-C; FLJ10186; FLN-C; gamma filamin; Gamma-filamin
Gene Aliases: 1110055E19Rik; ABP-280; ABP280A; ABPA; ABPL; FLN2; FLNC; MFM5; MPD4
UniProt ID: (Human) Q14315, (Mouse) Q8VHX6
Entrez Gene ID: (Human) 2318, (Mouse) 68794
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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