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Invitrogen
Flotillin 1 Polyclonal Antibody
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Flotillin 1 Antibody (PA5-95112) in IHC (P)
Immunohistochemistry (Paraffin) analysis of Flotillin 1 in paraffin-embedded section of human stomach camcer tissue using Flotillin 1 Polyclonal Antibody (Product # PA5-95112). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilut... View More
Product Details
PA5-95112
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Flotillin 1 (219-234aa KKAAYDIEVNTRRAQA).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806918
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human A431 whole cell lysates, human U251 whole cell lysates, human PC-3 whole cell lysates, human Hacat whole cell lysates, rat brain tissue lysates, rat skin tissue lysates, mouse brain tissue lysates, mouse skin tissue lysates. IHC: human stomach camcer, mouse brain, rat brain IP: A431 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DADB-118P11.2; Flotillin-1; integral membrane component of caveolae; OTTHUMP00000164855; REG-2; Reggie-2
Gene Aliases: FLOT1; Rareg; Reg2; reggie-2
UniProt ID: (Human) O75955, (Mouse) O08917, (Rat) Q9Z1E1
Entrez Gene ID: (Human) 10211, (Mouse) 14251, (Rat) 64665
membrane raft assembly
positive regulation of cytokine production
positive regulation of protein phosphorylation
regulation of receptor internalization
endocytosis
axonogenesis
axon guidance
extracellular matrix disassembly
positive regulation of protein binding
positive regulation of interferon-beta production
dsRNA transport
positive regulation of heterotypic cell-cell adhesion
positive regulation of toll-like receptor 3 signaling pathway
response to endoplasmic reticulum stress
regulation of Rho protein signal transduction
plasma membrane raft assembly
positive regulation of endocytosis
positive regulation of skeletal muscle tissue development
protein homooligomerization
positive regulation of cell adhesion molecule production
protein kinase C signaling
cellular response to exogenous dsRNA
protein localization to plasma membrane
establishment of protein localization to plasma membrane
positive regulation of myoblast fusion
positive regulation of cell junction assembly
protein localization to membrane raft
positive regulation of cell-cell adhesion mediated by cadherin
positive regulation of synaptic transmission, dopaminergic
regulation of toll-like receptor 4 signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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