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Invitrogen
Fra2 Polyclonal Antibody
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FIGURE: 1 / 1
Fra2 Antibody (PA5-95286) in WB
Western blot analysis of Fra2 in Lane 1: rat lung tissue lysate (50 µg), Lane 2: HEPG2 whole cell lysate (40 µg), Lane 3: A549 whole cell lysate (40 µg), Lane 4: SW620 whole cell lysate (40 µg). Samples were incubated with Fra2 polyclonal antibody (Product # PA5-95286).
Product Details
PA5-95286
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human FRA2 (96-127aa ALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKR).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807090
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Lung Tissue, HEPG2 whole cell, A549 whole cell, SW620 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FOS like 2, AP-1 trancription factor subunit; FOS like antigen 2; FOS-like antigen 2; Fos-related antigen 2; FRA-2
Gene Aliases: FOSL2; Fra-2; FRA2
UniProt ID: (Human) P15408, (Rat) P51145
Entrez Gene ID: (Human) 2355, (Rat) 25446
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
double-stranded DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
conditioned taste aversion
response to hypoxia
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
female pregnancy
aging
circadian rhythm
response to cold
response to light stimulus
response to mechanical stimulus
response to toxic substance
photoperiodism
response to organic cyclic compound
sleep
response to estradiol
response to progesterone
response to cytokine
response to immobilization stress
response to peptide hormone
positive regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
response to cAMP
keratinocyte development
transcription, DNA-templated
cell death
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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