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Osenses
Frataxin Polyclonal Antibody
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Product Details
OSF00008W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mature mouse Frataxin conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Frataxin.
Target Information
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Frataxin, mitochondrial; Friedreich ataxia; Fxn
Gene Aliases: FA; FARR; Frda; Fxn; RGD1565754; X25
UniProt ID: (Mouse) O35943
Entrez Gene ID: (Rat) 499335, (Mouse) 14297
oxidative phosphorylation
heme biosynthetic process
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
response to organic cyclic compound
iron-sulfur cluster assembly
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
response to drug
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of axon extension
negative regulation of organ growth
positive regulation of transferase activity
positive regulation of lyase activity
positive regulation of oxidoreductase activity
oxidation-reduction process
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
transport
iron ion homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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