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NeoBiotechnologies
Frataxin (Mitochondrial Marker) Monoclonal Antibody (rFXN/2124)
Product Details
2395-MSM6-P0
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
rFXN/2124
Immunogen
Recombinant human Frataxin protein fragment (around aa 57-210).
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Target Information
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Frataxin, mitochondrial; Friedreich ataxia protein; Fxn
Gene Aliases: CyaY; FA; FARR; FRDA; FXN; X25
UniProt ID: (Human) Q16595
Entrez Gene ID: (Human) 2395
oxidative phosphorylation
heme biosynthetic process
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
negative regulation of apoptotic process
positive regulation of catalytic activity
small molecule metabolic process
negative regulation of organ growth
positive regulation of lyase activity
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
positive regulation of succinate dehydrogenase activity
positive regulation of aconitate hydratase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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