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Immunogen sequence: IQAYPEAFCS ILCHKPESLS AKILSELFTV HTLPDVKALG FWNSYLQAVE DGKSTTTMED ILIFATGCSS IPPAGFKPTP SIECLHVDFP VGNKCNNCLA IPITNTYKEF QENMDFTIRN T
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 81%.
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G2/M phase-specific E3 ubiquitin-protein ligase; G2/M phase-specific HECT-type E3 ubiquitin transferase; G2/M-phase specific E3 ubiquitin ligase; PHD finger protein 7B
Gene Aliases: G2E3; KIAA1333; PHF7B
UniProt ID: (Human) Q7L622
Entrez Gene ID: (Human) 55632
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