Product References
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.
Antioxidants & redox signaling
Liu Y,Wang Y,Lin Z,Kang R,Tang D,Liu J
Sat Jul 01 00:00:00 UTC 2023
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang C,Lu T,Liu M,Yuan X,Li D,Zhang J,Zhou L,Xu M
Wed Mar 01 00:00:00 UTC 2023
Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation.
Molecular cancer research : MCR
Qiao R,Wei M,Chen H,Zhang X,Zhang J,Gao L,Ma H,Wang Y,Li L
Tue Aug 01 00:00:00 UTC 2023
Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver.
Toxicological sciences : an official journal of the Society of Toxicology
Kimura Y,Ekuban FA,Zong C,Sugie S,Zhang X,Itoh K,Yamamoto M,Ichihara S,Ohsako S,Ichihara G
Tue Aug 29 00:00:00 UTC 2023
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Communications biology
Tan J,Wang W,Liu X,Xu J,Che Y,Liu Y,Hu J,Hu L,Li J,Zhou Q
Mon Jun 05 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 UTC 2023
Metformin attenuates sevoflurane-induced neurogenesis damage and cognitive impairment: involvement of the Nrf2/G6PD pathway.
Metabolic brain disease
Fan P,Lu Y,Wei H,Wang K,Jia P,Zhang Y,Zhang Y,Wang T,Yang L,Zhao J,Zhang S,Lu H,Chen X,Liu Y,Zhang P
Tue Aug 01 00:00:00 UTC 2023
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang X,Gao L,Deng R,Peng Y,Wu S,Lu J,Liu X
Tue Aug 01 00:00:00 UTC 2023
Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang X,Gao L,Deng R,Peng Y,Wu S,Lu J,Liu X
Tue Aug 01 00:00:00 UTC 2023
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
International journal of biological sciences
Zhong C,Long Z,Yang T,Wang S,Zhong W,Hu F,Teoh JY,Lu J,Mao X
Tue Apr 18 00:00:00 UTC 2023
Cuproptosis regulator-mediated patterns associated with immune infiltration features and construction of cuproptosis-related signatures to guide immunotherapy.
Frontiers in immunology
Wang G,Xiao R,Zhao S,Sun L,Guo J,Li W,Zhang Y,Bian X,Qiu W,Wang S
Wed Feb 15 00:00:00 UTC 2023
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
Frontiers in oncology
Ye T,Lin L,Cao L,Huang W,Wei S,Shan Y,Zhang Z
Sat Jul 16 00:00:00 UTC 2022
Inhibition of STAT3 reverses Taxol-resistance in ovarian cancer by down-regulating G6PD expression in vitro.
Biochemical and biophysical research communications
Sheng H,Feng Q,Quan Q,Sheng X,Zhang P
Tue Aug 30 00:00:00 UTC 2022
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Journal of immunology (Baltimore, Md. : 1950)
Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN
Tue Nov 01 00:00:00 UTC 2022
G6PD-mediated increase in de novo NADP+ biosynthesis promotes antioxidant defense and tumor metastasis.
Science advances
Zhang Y,Xu Y,Lu W,Li J,Yu S,Brown EJ,Stanger BZ,Rabinowitz JD,Yang X
Fri Jul 22 00:00:00 UTC 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 UTC 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 UTC 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 UTC 2022
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Liu WC,Chuang HC,Chou CL,Lee YH,Chiu YJ,Wang YL,Chiu HW
Fri Apr 08 00:00:00 UTC 2022
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
The Journal of biological chemistry
Jin X,Li X,Li L,Zhong B,Hong Y,Niu J,Li B
Thu Dec 01 00:00:00 UTC 2022
Prognostic and predictive role of a metabolic rate-limiting enzyme signature in hepatocellular carcinoma.
Cell proliferation
Wang Z,Fu Y,Xia A,Chen C,Qu J,Xu G,Zou X,Wang Q,Wang S
Fri Oct 01 00:00:00 UTC 2021
Prognostic and predictive role of a metabolic rate-limiting enzyme signature in hepatocellular carcinoma.
Cell proliferation
Wang Z,Fu Y,Xia A,Chen C,Qu J,Xu G,Zou X,Wang Q,Wang S
Fri Oct 01 00:00:00 UTC 2021
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).
Cell proliferation
Zhang X,Gao F,Ai H,Wang S,Song Z,Zheng L,Wang G,Sun Y,Bao Y
Thu Apr 01 00:00:00 UTC 2021
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).
Cell proliferation
Zhang X,Gao F,Ai H,Wang S,Song Z,Zheng L,Wang G,Sun Y,Bao Y
Thu Apr 01 00:00:00 UTC 2021
TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).
Cell proliferation
Zhang X,Gao F,Ai H,Wang S,Song Z,Zheng L,Wang G,Sun Y,Bao Y
Thu Apr 01 00:00:00 UTC 2021
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3.
Biochemical pharmacology
Sun M,Sheng H,Wu T,Song J,Sun H,Wang Y,Wang J,Li Z,Zhao H,Tan J,Li Y,Chen G,Huang Q,Zhang Y,Lan B,Liu S,Shan C,Zhang S
Fri Oct 01 00:00:00 UTC 2021
Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal.
International journal of molecular sciences
Ito A,Nasako H,Akizuki R,Takashina Y,Eguchi H,Matsunaga T,Yoshino Y,Endo S,Ikari A
Sat Jun 19 00:00:00 UTC 2021
Establishing and validating a pathway prognostic signature in pancreatic cancer based on miRNA and mRNA sets using GSVA.
Aging
Zhang J,Gu J,Guo S,Huang W,Zheng Y,Wang X,Zhang T,Zhao W,Ni B,Fan Y,Wang H
Tue Nov 10 00:00:00 UTC 2020
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1.
Biochemical pharmacology
Feng Q,Li X,Sun W,Sun M,Li Z,Sheng H,Xie F,Zhang S,Shan C
Sat Aug 01 00:00:00 UTC 2020
4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.
Cell death & disease
Shan C,Lu Z,Li Z,Sheng H,Fan J,Qi Q,Liu S,Zhang S
Mon Jul 08 00:00:00 UTC 2019
ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells.
International journal of oncology
Xu Y,Gao W,Zhang Y,Wu S,Liu Y,Deng X,Xie L,Yang J,Yu H,Su J,Sun L
Sat Sep 01 00:00:00 UTC 2018
ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells.
International journal of oncology
Xu Y,Gao W,Zhang Y,Wu S,Liu Y,Deng X,Xie L,Yang J,Yu H,Su J,Sun L
Sat Sep 01 00:00:00 UTC 2018
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Oncotarget
Gu Z,Zhang H,Li Y,Shen S,Yin X,Zhang W,Cheng R,Zhang Y,Zhang X,Chen H,Huang B,Cao Y
Tue Dec 26 00:00:00 UTC 2017
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Oncotarget
Gu Z,Zhang H,Li Y,Shen S,Yin X,Zhang W,Cheng R,Zhang Y,Zhang X,Chen H,Huang B,Cao Y
Tue Dec 26 00:00:00 UTC 2017
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.
Nature communications
Ma X,Wang L,Huang D,Li Y,Yang D,Li T,Li F,Sun L,Wei H,He K,Yu F,Zhao D,Hu L,Xing S,Liu Z,Li K,Guo J,Yang Z,Pan X,Li A,Shi Y,Wang J,Gao P,Zhang H
Wed Nov 15 00:00:00 UTC 2017
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.
Nature communications
Ma X,Wang L,Huang D,Li Y,Yang D,Li T,Li F,Sun L,Wei H,He K,Yu F,Zhao D,Hu L,Xing S,Liu Z,Li K,Guo J,Yang Z,Pan X,Li A,Shi Y,Wang J,Gao P,Zhang H
Wed Nov 15 00:00:00 UTC 2017
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.
Nature communications
Ma X,Wang L,Huang D,Li Y,Yang D,Li T,Li F,Sun L,Wei H,He K,Yu F,Zhao D,Hu L,Xing S,Liu Z,Li K,Guo J,Yang Z,Pan X,Li A,Shi Y,Wang J,Gao P,Zhang H
Wed Nov 15 00:00:00 UTC 2017
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.
Nature communications
Ma X,Wang L,Huang D,Li Y,Yang D,Li T,Li F,Sun L,Wei H,He K,Yu F,Zhao D,Hu L,Xing S,Liu Z,Li K,Guo J,Yang Z,Pan X,Li A,Shi Y,Wang J,Gao P,Zhang H
Wed Nov 15 00:00:00 UTC 2017
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 UTC 2016
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Scientific reports
Zheng ZG,Xu H,Suo SS,Xu XL,Ni MW,Gu LH,Chen W,Wang LY,Zhao Y,Tian B,Hua YJ
Thu May 19 00:00:00 UTC 2016
