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Invitrogen
G6PD Polyclonal Antibody
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Product Details
PA5-145333
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Rat G6PD protein, Met1-Leu515 (Accession #P05370)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093556
Target Information
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G6PD; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase X-linked
Gene Aliases: G28A; G6pd; G6pd-1; G6pdx; Gpdx
UniProt ID: (Rat) P05370, (Mouse) Q00612
Entrez Gene ID: (Rat) 24377, (Mouse) 14381
cytokine production
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
carbohydrate metabolic process
glucose metabolic process
pentose-phosphate shunt
cholesterol biosynthetic process
NADP metabolic process
NADPH regeneration
NADP biosynthetic process
glutathione metabolic process
response to oxidative stress
pentose-phosphate shunt, oxidative branch
negative regulation of protein glutathionylation
pentose biosynthetic process
interleukin-10 production
interleukin-12 production
cellular response to oxidative stress
regulation of multicellular organism growth
erythrocyte maturation
regulation of neuron apoptotic process
response to ethanol
ribose phosphate biosynthetic process
erythrocyte development
glucose 6-phosphate metabolic process
oxidation-reduction process
response to organic cyclic compound
substantia nigra development
response to food
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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