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Product Details
22439-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GABARAP Fusion Protein Ag18209 (1-117 aa encoded by BC106749)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKFVYKEEH PFEKRRSEGE KIRKKYPDRV PVIVEKAPKA RIGDLDKKKY LVPSDLTVGQ FYFLIRKRIH LRAEDALFFF VNNVIPPTSA TMGQLYQEHH EEDFFLYIAY SDESVYGL (1-117 aa encoded by BC106749)
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ25768; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; GABARAP a; Gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; hypothetical protein; MGC120154; MGC120155; MM46
Gene Aliases: ATG8A; FLC3B; GABARAP; GABARAP-a; HT004; MM46
UniProt ID: (Human) O95166, (Mouse) B1AR49
Entrez Gene ID: (Human) 11337, (Mouse) 56486
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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