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Invitrogen
GABARAP Polyclonal Antibody
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Product Details
PA1-4147
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues P(33) H L P R P H P R V P P H P S S E R R A V Y(54) of the mouse and rat GABA R1 subunit.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2108010
Product Specific Information
PA1-4147 detects GABA Receptor Associated Protein in human, rat, mouse, bovine, and non-human primate samples.
PA1-4147 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~116 kDa protein representing GABA Receptor Associated Protein in brain lysate.
The PA1-4147 immunogen is a synthetic peptide corresponding to residues P(33) H L P R P H P R V P P H P S S E R R A V Y(54) of the mouse and rat GABA R1 subunit.
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ25768; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; GABARAP a; gamma-aminobutyric acid receptor associated protein; Gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; hypothetical protein; MGC120154; MGC120155; MM46
Gene Aliases: ATG8A; BOS_18670; FLC3B; GABARAP; GABARAP-a; HT004; MM46
UniProt ID: (Human) O95166, (Bovine) Q9GJW7, (Rat) P60517, (Mouse) B1AR49
Entrez Gene ID: (Human) 11337, (Bovine) 327715, (Rat) 58974, (Mouse) 56486
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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