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Immunogen sequence: PGTTGQGES RRQEPGDFVK QDIGGLSPKH APDIPDDSTD NITIFTRILD RLLDGYDNRL RPGLGDAVTE VKTDIYVTSF GPVSDTDMEY TIDVFFRQTW HDERLKFDGP MKILPLNNLL ASKIWTPDTF FHNGKKSVAH NMTTPNKLLR LVDNGTLPYT MRLTIHAECP MHLEDFPMDV HACPLKFGSY AYTTAEVVYS WTLGKNKSVE VAQDGSRLNQ YDLLGHVVGT EIIRSSTGEY VVMTTHFHLK RKIGYFVIQT (24-282 aa encoded by BC028629)
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GABA(A) receptor; GABA(A) receptor subunit alpha-3; GABA(A) receptor, alpha 3; GABA-A receptor alpha-3 subunit; GABAAR subunit alpha-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 3; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3; Gamma-aminobutyric acid receptor subunit alpha-3; gamma-aminobutyric acid receptor, subunit alpha 3; Gamma-animobutyric acid (GABA) A receptor alpha 3; Gamma-animobutyric acid (GABA) A receptor, alpha 3; MGC33793
Gene Aliases: Gabra-3; GABRA3
UniProt ID: (Human) P34903, (Mouse) P26049, (Rat) P20236
Entrez Gene ID: (Human) 2556, (Mouse) 14396, (Rat) 24947
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