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Invitrogen
GABRA3 Polyclonal Antibody
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GABRA3 Antibody (PA5-88192) in WB
Western blot analysis of GABRA3 in extracts of various cell lines. Samples were incubated with GABRA3 Polyclonal antibody (Product # PA5-88192) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-88192
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-276 of human GABRA3 (NP_0007991)
Conjugate
Form
Liquid
Concentration
1.48 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804732
Product Specific Information
Immunogen sequence: QGESRRQEPG DFVKQDIGGL SPKHAPDIPD DSTDNITIFT RILDRLLDGY DNRLRPGLGD AVTEVKTDIY VTSFGPVSDT DMEYTIDVFF RQTWHDERLK FDGPMKILPL NNLLASKIWT PDTFFHNGKK SVAHNMTTPN KLLRLVDNGT LLYTMRLTIH AECPMHLEDF PMDVHACPLK FGSYAYTTAE VVYSWTLGKN KSVEVAQDGS RLNQYDLLGH VVGTEIIRSS TGEYVVMTTH FHLKRKIG; Positive Samples: SH-SY5Y, Mouse kidney, Rat liver; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor; GABA(A) receptor subunit alpha-3; GABA(A) receptor, alpha 3; GABA-A receptor alpha-3 subunit; GABAAR subunit alpha-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 3; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3; Gamma-aminobutyric acid receptor subunit alpha-3; gamma-aminobutyric acid receptor, subunit alpha 3; Gamma-animobutyric acid (GABA) A receptor alpha 3; Gamma-animobutyric acid (GABA) A receptor, alpha 3; MGC33793
Gene Aliases: Gabra-3; GABRA3
UniProt ID: (Human) P34903, (Mouse) P26049, (Rat) P20236
Entrez Gene ID: (Human) 2556, (Mouse) 14396, (Rat) 24947
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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