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Invitrogen
GABRG1 Polyclonal Antibody
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GABRG1 Antibody (PA5-99317) in IHC (P)
Immunohistochemistry analysis of GABRG1 in human ovarian cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with GABRG1 polyclonal antibody (Product # PA5-99317) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99317
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GABRG1(Accession Q8N1C3), corresponding to amino acid residues S18-L68.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818250
Product Specific Information
Antibody detects endogenous levels of GABRG1.
Target Information
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GABAAR gamma1; GABAAR subunit gamma-1; Gabeg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 1; gamma-aminobutyric acid A receptor, gamma 1; Gamma-aminobutyric acid receptor subunit gamma-1
Gene Aliases: GabaA; GabaA/BZ; GABRG1
UniProt ID: (Human) Q8N1C3, (Rat) P23574, (Mouse) Q9R0Y8
Entrez Gene ID: (Human) 2565, (Rat) 140674, (Mouse) 14405
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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