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Invitrogen
GABRQ Polyclonal Antibody
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GABRQ Antibody (PA5-89095) in WB
Western blot analysis of GABRQ in extracts of Jurkat cells. Samples were incubated with GABRQ Polyclonal antibody (Product # PA5-89095) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89095
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human GABRQ (NP_0610283)
Conjugate
Form
Liquid
Concentration
2.53 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805351
Product Specific Information
Immunogen sequence: NYLFYSRGPR RQPRRHRRPR RVIARYRYQQ VVVGNVQDGL INVEDGVSSL PITPAQAPLA SPESLGSLTS TSEQAQLATS ESLSPLTSLS GQAPLATGES LSDLPSTSEQ ARHSYGVRFN GFQADDSIIP TEIRNRVEAH GHGVTHDHED SNESLSSDER HGHGPSGKPM LHHGEKGVQE AGWDLDDNND KSDCLAIKEQ FKCDTNSTWG LNDDELMAHG QEKDSSSESE DSCPPSPGCS FTEGFSFDLF N; Positive Samples: Jurkat; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor subunit theta; GABA(A) Theta; GABAAR subunit theta; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, theta; Gamma-aminobutyric acid receptor subunit theta
Gene Aliases: GABRQ; THETA
UniProt ID: (Human) Q9UN88
Entrez Gene ID: (Human) 55879
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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