Product References
Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling.
American journal of physiology. Heart and circulatory physiology
Yoshikawa S,Nagao M,Toh R,Shinohara M,Iino T,Irino Y,Nishimori M,Tanaka H,Satomi-Kobayashi S,Ishida T,Hirata KI
Sun May 01 00:00:00 UTC 2022
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
International journal of molecular sciences
Beręsewicz-Haller M,Krupska O,Bochomulski P,Dudzik D,Chęcińska A,Hilgier W,Barbas C,Zablocki K,Zablocka B
Sat Aug 07 00:00:00 UTC 2021
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
International journal of molecular sciences
Beręsewicz-Haller M,Krupska O,Bochomulski P,Dudzik D,Chęcińska A,Hilgier W,Barbas C,Zablocki K,Zablocka B
Sat Aug 07 00:00:00 UTC 2021
Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection.
Cell metabolism
Balmer ML,Ma EH,Thompson AJ,Epple R,Unterstab G,Lötscher J,Dehio P,Schürch CM,Warncke JD,Perrin G,Woischnig AK,Grählert J,Löliger J,Assmann N,Bantug GR,Schären OP,Khanna N,Egli A,Bubendorf L,Rentsch K,Hapfelmeier S,Jones RG,Hess C
Tue Sep 01 00:00:00 UTC 2020
Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism.
Cell stem cell
Sommerkamp P,Altamura S,Renders S,Narr A,Ladel L,Zeisberger P,Eiben PL,Fawaz M,Rieger MA,Cabezas-Wallscheid N,Trumpp A
Thu May 07 00:00:00 UTC 2020
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 UTC 2019
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 UTC 2019
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 UTC 2019
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
EBioMedicine
Li B,Cao Y,Meng G,Qian L,Xu T,Yan C,Luo O,Wang S,Wei J,Ding Y,Yu D
Tue Jan 01 00:00:00 UTC 2019
Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4+ T Cells.
AIDS research and human retroviruses
Hegedus A,Kavanagh Williamson M,Khan MB,Dias Zeidler J,Da Poian AT,El-Bacha T,Struys EA,Huthoff H
Fri Dec 01 00:00:00 UTC 2017
Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4+ T Cells.
AIDS research and human retroviruses
Hegedus A,Kavanagh Williamson M,Khan MB,Dias Zeidler J,Da Poian AT,El-Bacha T,Struys EA,Huthoff H
Fri Dec 01 00:00:00 UTC 2017
Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition.
PloS one
Lampa M,Arlt H,He T,Ospina B,Reeves J,Zhang B,Murtie J,Deng G,Barberis C,Hoffmann D,Cheng H,Pollard J,Winter C,Richon V,Garcia-Escheverria C,Adrian F,Wiederschain D,Srinivasan L
Tue Oct 31 00:00:00 UTC 2017
Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition.
PloS one
Lampa M,Arlt H,He T,Ospina B,Reeves J,Zhang B,Murtie J,Deng G,Barberis C,Hoffmann D,Cheng H,Pollard J,Winter C,Richon V,Garcia-Escheverria C,Adrian F,Wiederschain D,Srinivasan L
Tue Oct 31 00:00:00 UTC 2017
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
Scientific reports
Zacharias NM,McCullough C,Shanmugavelandy S,Lee J,Lee Y,Dutta P,McHenry J,Nguyen L,Norton W,Jones LW,Bhattacharya PK
Thu Nov 23 00:00:00 UTC 2017
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
Scientific reports
Zacharias NM,McCullough C,Shanmugavelandy S,Lee J,Lee Y,Dutta P,McHenry J,Nguyen L,Norton W,Jones LW,Bhattacharya PK
Thu Nov 23 00:00:00 UTC 2017
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
Scientific reports
Zacharias NM,McCullough C,Shanmugavelandy S,Lee J,Lee Y,Dutta P,McHenry J,Nguyen L,Norton W,Jones LW,Bhattacharya PK
Thu Nov 23 00:00:00 UTC 2017
Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation.
Oncotarget
Effenberger M,Bommert KS,Kunz V,Kruk J,Leich E,Rudelius M,Bargou R,Bommert K
Tue Oct 17 00:00:00 UTC 2017
Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation.
Oncotarget
Effenberger M,Bommert KS,Kunz V,Kruk J,Leich E,Rudelius M,Bargou R,Bommert K
Tue Oct 17 00:00:00 UTC 2017
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.
RNA (New York, N.Y.)
Masamha CP,Xia Z,Peart N,Collum S,Li W,Wagner EJ,Shyu AB
Wed Jun 01 00:00:00 UTC 2016
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.
RNA (New York, N.Y.)
Masamha CP,Xia Z,Peart N,Collum S,Li W,Wagner EJ,Shyu AB
Wed Jun 01 00:00:00 UTC 2016
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
PloS one
Sener Z,Cederkvist FH,Volchenkov R,Holen HL,Skålhegg BS
Wed Aug 02 00:00:00 UTC 2017
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
PloS one
Sener Z,Cederkvist FH,Volchenkov R,Holen HL,Skålhegg BS
Wed Aug 02 00:00:00 UTC 2017
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
PloS one
Sener Z,Cederkvist FH,Volchenkov R,Holen HL,Skålhegg BS
Wed Aug 02 00:00:00 UTC 2017
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
PloS one
Sener Z,Cederkvist FH,Volchenkov R,Holen HL,Skålhegg BS
Wed Aug 02 00:00:00 UTC 2017
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Oncotarget
Matre P,Velez J,Jacamo R,Qi Y,Su X,Cai T,Chan SM,Lodi A,Sweeney SR,Ma H,Davis RE,Baran N,Haferlach T,Su X,Flores ER,Gonzalez D,Konoplev S,Samudio I,DiNardo C,Majeti R,Schimmer AD,Li W,Wang T,Tiziani S,Konopleva M
Tue Nov 29 00:00:00 UTC 2016
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Oncotarget
Matre P,Velez J,Jacamo R,Qi Y,Su X,Cai T,Chan SM,Lodi A,Sweeney SR,Ma H,Davis RE,Baran N,Haferlach T,Su X,Flores ER,Gonzalez D,Konoplev S,Samudio I,DiNardo C,Majeti R,Schimmer AD,Li W,Wang T,Tiziani S,Konopleva M
Tue Nov 29 00:00:00 UTC 2016
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Blood
Jacque N,Ronchetti AM,Larrue C,Meunier G,Birsen R,Willems L,Saland E,Decroocq J,Maciel TT,Lambert M,Poulain L,Hospital MA,Sujobert P,Joseph L,Chapuis N,Lacombe C,Moura IC,Demo S,Sarry JE,Recher C,Mayeux P,Tamburini J,Bouscary D
Thu Sep 10 00:00:00 UTC 2015
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Blood
Jacque N,Ronchetti AM,Larrue C,Meunier G,Birsen R,Willems L,Saland E,Decroocq J,Maciel TT,Lambert M,Poulain L,Hospital MA,Sujobert P,Joseph L,Chapuis N,Lacombe C,Moura IC,Demo S,Sarry JE,Recher C,Mayeux P,Tamburini J,Bouscary D
Thu Sep 10 00:00:00 UTC 2015
Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Molecular cancer therapeutics
Gross MI,Demo SD,Dennison JB,Chen L,Chernov-Rogan T,Goyal B,Janes JR,Laidig GJ,Lewis ER,Li J,Mackinnon AL,Parlati F,Rodriguez ML,Shwonek PJ,Sjogren EB,Stanton TF,Wang T,Yang J,Zhao F,Bennett MK
Tue Apr 01 00:00:00 UTC 2014
Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Molecular cancer therapeutics
Gross MI,Demo SD,Dennison JB,Chen L,Chernov-Rogan T,Goyal B,Janes JR,Laidig GJ,Lewis ER,Li J,Mackinnon AL,Parlati F,Rodriguez ML,Shwonek PJ,Sjogren EB,Stanton TF,Wang T,Yang J,Zhao F,Bennett MK
Tue Apr 01 00:00:00 UTC 2014
Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.
Oncotarget
Lee YZ,Yang CW,Chang HY,Hsu HY,Chen IS,Chang HS,Lee CH,Lee JC,Kumar CR,Qiu YQ,Chao YS,Lee SJ
Fri Aug 15 00:00:00 UTC 2014
Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.
Oncotarget
Lee YZ,Yang CW,Chang HY,Hsu HY,Chen IS,Chang HS,Lee CH,Lee JC,Kumar CR,Qiu YQ,Chao YS,Lee SJ
Fri Aug 15 00:00:00 UTC 2014
Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Szeliga M,Bogacińska-Karaś M,Różycka A,Hilgier W,Marquez J,Albrecht J
Sat Mar 01 00:00:00 UTC 2014
Silencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Szeliga M,Bogacińska-Karaś M,Różycka A,Hilgier W,Marquez J,Albrecht J
Sat Mar 01 00:00:00 UTC 2014
