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Product Details
12897-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GALNT4 Fusion Protein Ag3590 (230-578 aa encoded by BC036390)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CECNSGWLE PLLERIGRDE TAVVCPVIDT IDWNTFEFYM QIGEPMIGGF DWRLTFQWHS VPKQERDRRI SRIDPIRSPT MAGGLFAVSK KYFQYLGTYD TGMEVWGGEN LELSFRVWQC GGKLEIHPCS HVGHVFPKRA PYARPNFLQN TARAAEVWMD EYKEHFYNRN PPARKEAYGD ISERKLLRER LRCKSFDWYL KNVFPNLHVP EDRPGWHGAI RSRGISSECL DYNSPDNNPT GANLSLFGCH GQGGNQFFEY TSNKEIRFNS VTELCAEVPE QKNYVGMQNC PKDGFPVPAN IIWHFKEDGT IFHPHSGLCL SAYRTPEGRP DVQMRTCDAL DKNQIWSFEK (230-578 aa encoded by BC036390)
Target Information
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GalNAc-T4; Polypeptide GalNAc transferase 4; polypeptide GalNAc transferase-T4; Polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4; ppGaNTase-T4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
Gene Aliases: AV011803; GALNAC-T4; GALNACT4; GALNT4
UniProt ID: (Human) Q8N4A0, (Mouse) O08832
Entrez Gene ID: (Human) 8693, (Rat) 500826, (Mouse) 14426
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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