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Invitrogen
GALR3 Polyclonal Antibody
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Product Details
PA5-28747
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide encompassing a sequence within the Extracellular domain of human GALR3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.72 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546223
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse eye, mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts. GALR3 has been reported in brain, testis, adrenal gland, and pancreas. An EST has been isolated from an ovarian thecoma fibroma library.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gal receptor-3; Gal-r3; Gal3 receptor; GAL3-R; Galanin r3 receptor; Galanin receptor type 3; galanin receptor, family member 3; GALR-3; OTTHUMP00000028820
Gene Aliases: GALNR3; GALR3
UniProt ID: (Human) O60755, (Mouse) O88853, (Rat) O88626
Entrez Gene ID: (Human) 8484, (Mouse) 14429, (Rat) 29235
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
negative regulation of cAMP biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
negative regulation of adenylate cyclase activity
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
learning or memory
feeding behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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