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Immunogen sequence: MSRSGTDPQ QRQQASEADA AAATFRANDH QHIRYNPLQD EWVLVSAHRM KRPWQGQVEP QLLKTVPRHD PLNPLCPGAI RANGEVNPQY DSTFLFDNDF PALQPDAPSP GPSDHPLFQA KSARGVCKVM CFHPWSDVTL PLMSVPEIRA VVDAWASVTE ELGAQYPWVQ IFENKGAMMG CSNPHPHCQV WASSFLPDIA QREERSQQAY KSQHGEPLLM EYSRQELLRK ERLVLTSEHW LVLVPFWATW PYQTLLLPRR HVRRLPELTP AERDDLASIM KKLLTKYDNL FETSFPYSMG WHGAPTGSEA GANWDHWQLH AHYYPPLLRS ATVRKFMVGY EMLAQAQRDL TPEQAAERLR ALPEVHYHLG QKDRETATIA (1-379 aa encoded by BC015045)
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Gal-1-P uridylyltransferase; galactose-1-phosphate uridyl transferase; Galactose-1-phosphate uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase
Gene Aliases: GALT
UniProt ID: (Human) P07902
Entrez Gene ID: (Human) 2592
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