Invitrogen

GAPDH Polyclonal Antibody

FIGURE: 1 / 20

GAPDH Antibody (PA1-988) in WB

Western blot analysis was performed on whole cell extracts (30 µg lysate) of A549 (Lane 1), COS-7 (Lane 2), MDCK (Lane 3), HT-29 (Lane 4), C2C12 (Lane 5), PC-12 (Lane 6), U-2 OS (Lane 7) and tissue extract (30 µg lysate) of Rat Testis (Lane 8), Mouse Liver (Lane 9). The blot was probed with Anti-GAPDH Polyclonal Antibody (Product # PA1-988, 1:500 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 37 kDa band c... View More

Product Image Gallery

GAPDH Antibody — FIG 1 . RNAi-based assay to identify host factors required for intracellular survival of Y. pestis . To determine whether reproducible RNAi could be achieved in RAW264.7 macrophages, cells were reverse transfected with siRNAs targeting indicated genes. (A and B) Forty-eight hours posttransfection, cells ( n = 3) were harvested for RNA isolation and qRT-PCR (data represent the level of gene expression compared to the level for the scrambled siRNA control) (A) or protein isolation for Western blot analysis (beta-actin was used as a loading control) (B). alpha-GAPDH, anti-GAPDH antibody; alpha-betaactin, anti-betaactin antibody. To demonstrate that the Y. pestis CO92 pCD1 (-) Lux PtolC bioreporter accurately represents intracellular bacterial numbers, RAW264.7 macrophages were infected with Y. pestis CO92 pCD1 (-) Lux PtolC at the indicated MOIs ( n = 12), and extracellular bacteria were killed with gentamicin. (C) Bioluminescence (in relative light units [RLU]) of intracellular bacteria was determined at 1, 4, 8, and 18 h postinfection. (D) At 18 h, cells from each MOI ( n = 3) were lysed, and bacterial numbers (CFU) were determined and compared to 18-h bioluminescence (in RLU). (E) To demonstrate that RNAi targeting specific genes could impact the intracellular survival of Y. pestis , RAW264.7 macrophages were transfected with siRNAs targeting Rab2A or COPbeta1. Forty-eight hours posttransfection, macrophages were infected with Y. pestis CO92 pCD1 (-) Lux PtolC (MOI of 10). Ex {KD}

Product Details

PA1-988

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

View 33 publications 33 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Human, Mouse, Non-human primate, Rat

Published species

Bovine, Hamster, Human, Mouse, Non-human primate, Rat, Rhesus monkey

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide: V(4) K V G V N G F G R I G R L V(18)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2107310

Product Specific Information

PA1-988 detects rat GAPDH in human HeLa cell lysates and mouse and rat tissues..

PA1-988 has been used successfully in Western blotting. By Western blot this antibody specifically detects a ~36 kDa protein representing GAPDH.

PA1-988 immunizing peptide corresponds to amino acid residues 4-18 from human GAPDH.

Target Information

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Subthalamic nucleus stimulation attenuates motor seizures via modulating the nigral orexin pathway.

Frontiers in neuroscience

Xue T,Wang S,Chen S,Wang H,Liu C,Shi L,Bai Y,Zhang C,Han C,Zhang J

PA1-988 was used in Western Blotting to investigate whether and how subthalamic nucleus inputs to the SNr regulate seizures and the role of the orexin pathway in this process.

Tue May 23 00:00:00 UTC 2023

Cacna2d2 inhibits axonal regeneration following surgical decompression in a rat model of cervical spondylotic myelopathy.

BMC neuroscience

Liu P,Li X,Liu J,Zhang H,You Z,Zhang J

PA1-988 was used in Western Blotting to show that inhibition of α2δ2 could enhance axonal recovery in anterior horn of damaged spinal cord induced by CSM after surgical decompression, providing a potential method for promoting axon regeneration following surgery.

Fri Jul 01 00:00:00 UTC 2022

Autophagy Alteration in ApoA-I Related Systemic Amyloidosis.

International journal of molecular sciences

Del Giudice R,Imbimbo P,Pietrocola F,Martins I,De Palma FDE,Bravo-San Pedro JM,Kroemer G,Maiuri MC,Monti DM

PA1-988 was used in Western Blotting to describe that the autophagic process is inhibited in the presence of the L75P-ApoA-I amyloidogenic variant in stably transfected human hepatocyte carcinoma cells.

Wed Mar 23 00:00:00 UTC 2022

CircRNA circYY1 (hsa_circ_0101187) Modulates Cell Glycolysis and Malignancy Through Regulating YY1 Expression by Sponging miR-769-3p in Breast Cancer.

Cancer management and research

Zhang X,Li J,Feng Q

PA1-988 was used in Western Blot to conclude that CircYY1 promoted glycolysis and tumor growth via increasing YY1 expression through sponging miR-769-3p in BC, offering a promising therapeutic target and prognostic biomarker for BC.

Wed Apr 20 00:00:00 UTC 2022

Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates.

Nature communications

Costa-Verdera H,Collaud F,Riling CR,Sellier P,Nordin JML,Preston GM,Cagin U,Fabregue J,Barral S,Moya-Nilges M,Krijnse-Locker J,van Wittenberghe L,Daniele N,Gjata B,Cosette J,Abad C,Simon-Sola M,Charles S,Li M,Crosariol M,Antrilli T,Quinn WJ,Gross DA,Boyer O,Anguela XM,Armour SM,Colella P,Ronzitti G,Mingozzi F

PA1-988 was used in Western Blotting to compare the efficacy of hepatic gene transfer with adeno-associated virus (AAV) vectors expressing secretable acid alpha-glucosidase with long-term enzyme replacement therapy.

Thu Nov 04 00:00:00 UTC 2021

Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates.

Nature communications

Thu Nov 04 00:00:00 UTC 2021

Chondroitin polymerizing factor promotes breast carcinoma cell proliferation, invasion and migration and affects expression of epithelial-mesenchymal transition-related markers.

FEBS open bio

Li Y,Gong H,Feng L,Mao D,Xiao Y,Wang Y,Huang L

PA1-988 was used in Western Blotting to investigate the role of CHPF in breast carcinoma (BRCA) and its underlying mechanism.

Mon Feb 01 00:00:00 UTC 2021

SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.

Autophagy

Salazar G,Cullen A,Huang J,Zhao Y,Serino A,Hilenski L,Patrushev N,Forouzandeh F,Hwang HS

PA1-988 was used in Western Blot to investigate the role of the mitochondrial regulator PPARGC1A and SQSTM1/p62 in autophagy and senescence.

Mon Jun 01 00:00:00 UTC 2020

Small molecular compounds efficiently convert human fibroblasts directly into neurons.

Molecular medicine reports

Yang J,Cao H,Guo S,Zhu H,Tao H,Zhang L,Chen Z,Sun T,Chi S,Hu Q

Published figure using GAPDH polyclonal antibody (Product # PA1-988) in Western Blot

Tue Dec 01 00:00:00 UTC 2020

DACH1, a novel target of miR-218, participates in the regulation of cell viability, apoptosis, inflammatory response, and epithelial-mesenchymal transition process in renal tubule cells treated by high-glucose.

Renal failure

Zhang YL,Wang JM,Yin H,Wang SB,He CL,Liu J

PA1-988 was used in Western Blotting to assess the functional role of miR-218/dachshund family transcription factor 1 (DACH1) in diabetic kidney disease (DKD) and investigate its possible molecular mechanism.

Sun Nov 01 00:00:00 UTC 2020

Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?

Biomolecules

Deshpande A,Vinayakamoorthy RM,Garg BK,Thummapudi JP,Oza G,Adhikari K,Agarwal A,Dalvi P,Iyer S,Thulasi Raman S,Ramesh V,Rameshbabu A,Rezvaya A,Sukumaran S,Swaminathan S,Tilak B,Wang Z,Tran PV,Loring RH

PA1-988 was used in Western Blotting to find mouse macrophages bind αBGT but lack NACHO.

Thu Mar 19 00:00:00 UTC 2020

Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects.

EBioMedicine

Colella P,Sellier P,Gomez MJ,Biferi MG,Tanniou G,Guerchet N,Cohen-Tannoudji M,Moya-Nilges M,van Wittenberghe L,Daniele N,Gjata B,Krijnse-Locker J,Collaud F,Simon-Sola M,Charles S,Cagin U,Mingozzi F

PA1-988 was used in Western Blotting to show that the genetic background impacts on the severity of respiratory function and neuroglial spinal cord defects in the acidalpha-glucosidase (GAA) KO mouse model of Pompe disease (PD).

Sun Nov 01 00:00:00 UTC 2020

Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects.

EBioMedicine

Colella P,Sellier P,Gomez MJ,Biferi MG,Tanniou G,Guerchet N,Cohen-Tannoudji M,Moya-Nilges M,van Wittenberghe L,Daniele N,Gjata B,Krijnse-Locker J,Collaud F,Simon-Sola M,Charles S,Cagin U,Mingozzi F

Sun Nov 01 00:00:00 UTC 2020

Inhibition of endogenous miR-23a/miR-377 in CHO cells enhances difficult-to-express recombinant lysosomal sulfatase activity.

Biotechnology progress

Amadi IM,Agrawal V,Christianson T,Bardliving C,Shamlou P,LeBowitz JH

PA1-988 was used in Western Blotting to demonstrate the importance of using miRNA to optimize the CHO cell line secreting DTE recombinant lysosomal sulfatase.

Fri May 01 00:00:00 UTC 2020

Engineered nanomedicine for neuroregeneration: light emitting diode-mediated superparamagnetic iron oxide-gold core-shell nanoparticles functionalized by nerve growth factor.

Nanomedicine : nanotechnology, biology, and medicine

Yuan M,Wang Y,Qin YX

PA1-988 was used in Western Blotting to report nerve growth factor functionalized superparamagnetic iron-oxide-gold core-shell nanoparticles (NGF-SPIO-Au NPs) as an engineered nanomedicine for non-invasive neuron regeneration when irradiated by a low-intensity light-emitting diode.

Tue Oct 01 00:00:00 UTC 2019

Deep morphological analysis of muscle biopsies from type III glycogenesis (GSDIII), debranching enzyme deficiency, revealed stereotyped vacuolar myopathy and autophagy impairment.

Acta neuropathologica communications

Laforêt P,Inoue M,Goillot E,Lefeuvre C,Cagin U,Streichenberger N,Leonard-Louis S,Brochier G,Madelaine A,Labasse C,Hedberg-Oldfors C,Krag T,Jauze L,Fabregue J,Labrune P,Milisenda J,Nadaj-Pakleza A,Sacconi S,Mingozzi F,Ronzitti G,Petit F,Schoser B,Oldfors A,Vissing J,Romero NB,Nishino I,Malfatti E

PA1-988 was used in Western Blotting to characterise the morphological phenotype in glycogen storage disorder type III muscle and demonstrated dysfunctional autophagy in GSDIII human samples.

Mon Oct 28 00:00:00 UTC 2019

Downregulation of microRNA-205 inhibits cell invasion and angiogenesis of cervical cancer through TSLC1-mediated Akt signaling pathway.

Journal of cellular physiology

Zhang F,Liu J,Xie BB

PA1-988 was used in Western Blot to demonstrate that downregulated miR-205 inhibited cell invasion, migration, and angiogenesis in CC by inactivating the Akt signaling pathway via TSLC1 upregulation.

Thu Aug 01 00:00:00 UTC 2019

AAV Gene Transfer with Tandem Promoter Design Prevents Anti-transgene Immunity and Provides Persistent Efficacy in Neonate Pompe Mice.

Molecular therapy. Methods & clinical development

Colella P,Sellier P,Costa Verdera H,Puzzo F,van Wittenberghe L,Guerchet N,Daniele N,Gjata B,Marmier S,Charles S,Simon Sola M,Ragone I,Leborgne C,Collaud F,Mingozzi F

PA1-988 was used in Western Blotting to develop tandem promoter monocistronic expression cassettes that can provide combined hepatic and extra-hepatic tissue-specific transgene expression and prevent anti-transgene immunity.

Fri Mar 15 00:00:00 UTC 2019

BACE1 Inhibition Using 2'-OMePS Steric Blocking Antisense Oligonucleotides.

Genes

Chakravarthy M,Veedu RN

PA1-988 was used in Western Blotting to develop a novel antisense oligonucleotide (AO) that could efficiently downregulate the transcript of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) and partially inhibit the activity of the BACE1 protein.

Thu Sep 12 00:00:00 UTC 2019

Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen.

Brain research

Brewer AL,Liu S,Buhler AV,Shirachi DY,Quock RM

PA1-988 was used in Western Blotting to show neurotransmitter γ-aminobutyric acid A may be involved in hyperbaric oxygen-induced antinociception at the γ-aminobutyric acid A receptor.

Thu Nov 15 00:00:00 UTC 2018

Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen.

Brain research

Brewer AL,Liu S,Buhler AV,Shirachi DY,Quock RM

PA1-988 was used in Western Blotting to show neurotransmitter γ-aminobutyric acid A may be involved in hyperbaric oxygen-induced antinociception at the γ-aminobutyric acid A receptor.

Thu Nov 15 00:00:00 UTC 2018

Downregulation of ROS1 enhances the therapeutic efficacy of arsenic trioxide in acute myeloid leukemia cell lines.

Oncology letters

Li J

PA1-988 was used in Western Blotting to investigate the function of ROS proto-oncogene 1 receptor tyrosine kinase in regulating the migration and proliferation of acute myeloid leukaemia cells through Wnt/Β-catenin signalling, and in arsenic trioxide treatment.

Fri Jun 01 00:00:00 UTC 2018

Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages.

mBio

Connor MG,Pulsifer AR,Chung D,Rouchka EC,Ceresa BK,Lawrenz MB

Published figure using GAPDH polyclonal antibody (Product # PA1-988) in Western Blot

Tue Feb 20 00:00:00 UTC 2018

A role for proteolytic regulation of δ-catenin in remodeling a subpopulation of dendritic spines in the rodent brain.

The Journal of biological chemistry

Yuan L,Singh D,Buescher JL,Arikkath J

PA1-988 was used in Western Blotting to conclude that by undergoing cleavage, δ-catenin differentially regulates the densities of subpopulations of dendritic spines and contributes to proper neural circuit wiring in the developing brain.

Fri Jul 20 00:00:00 UTC 2018

(-)-Epicatechin induces physiological cardiac growth by activation of the PI3K/Akt pathway in mice.

Molecular nutrition & food research

De Los Santos S,García-Pérez V,Hernández-Reséndiz S,Palma-Flores C,González-Gutiérrez CJ,Zazueta C,Canto P,Coral-Vázquez RM

PA1988 was used in western blot to evaluate the effects of epicatechin in the normal heart

Wed Feb 01 00:00:00 UTC 2017

Evaluating Commercially Available Antibodies for Rat α7 Nicotinic Acetylcholine Receptors.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Garg BK,Loring RH

PA1-988 was used in Western Blot to evaluate commercially available antibodies for rat α7 nicotinic acetylcholine receptors.

Fri Sep 01 00:00:00 UTC 2017

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.

Acta neuropathologica communications

Longo F,Mercatelli D,Novello S,Arcuri L,Brugnoli A,Vincenzi F,Russo I,Berti G,Mabrouk OS,Kennedy RT,Shimshek DR,Varani K,Bubacco L,Greggio E,Morari M

PA1988 was used in western blot to elucidate the effects of mutations in leucine-rich repeat kinase 2 on nigro0striatal dopamine neurons

Tue Mar 14 00:00:00 UTC 2017

MiR-132 regulates osteogenic differentiation via downregulating Sirtuin1 in a peroxisome proliferator-activated receptor β/δ-dependent manner.

Biochemical and biophysical research communications

Gong K,Qu B,Liao D,Liu D,Wang C,Zhou J,Pan X

PA1-988 was used in western blot to elucidate mechanisms by which miR-132 regulates osteogenic differentiation

Fri Sep 09 00:00:00 UTC 2016

Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor γ in MC3T3-E1 cells.

Biochemical and biophysical research communications

Qu B,Ma Y,Yan M,Gong K,Liang F,Deng S,Jiang K,Ma Z,Pan X

PA1-988 was used in western blot to investigate the molecular mechanism of Sirt1 in osteogenic differentiation

Fri Sep 09 00:00:00 UTC 2016

Metabolic Response to Heat Stress in Late-Pregnant and Early Lactation Dairy Cows: Implications to Liver-Muscle Crosstalk.

PloS one

Koch F,Lamp O,Eslamizad M,Weitzel J,Kuhla B

PA1-988 was used in western blot study feed intake and heat stress-related effects in cows

Mon Aug 07 00:00:00 UTC 2017

Registered report: A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.

eLife

Haven B,Heilig E,Donham C,Settles M,Vasilevsky N,Owen K

PA1-988 was used in western blot to discuss the findings of The Reproducibility Project: Cancer Biology

Tue Feb 23 00:00:00 UTC 2016

Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells.

International journal of molecular medicine

Goutzourelas N,Stagos D,Housmekeridou A,Karapouliou C,Kerasioti E,Aligiannis N,Skaltsounis AL,Spandidos DA,Tsatsakis AM,Kouretas D

Published figure using GAPDH polyclonal antibody (Product # PA1-988) in Western Blot

Sat Aug 01 00:00:00 UTC 2015

Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance.

PloS one

Verduzco D,Lloyd M,Xu L,Ibrahim-Hashim A,Balagurunathan Y,Gatenby RA,Gillies RJ

PA1-988 was used in western blot to identify genetic alterations and corresponding stable phenotypes that develop in cancer cells following cyclic hypoxia

Wed Feb 24 00:00:00 UTC 2016

Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model.

Human gene therapy

Ling C,Wang Y,Zhang Y,Ejjigani A,Yin Z,Lu Y,Wang L,Wang M,Li J,Hu Z,Aslanidi GV,Zhong L,Gao G,Srivastava A,Ling C

PA1-988 was used in western blot to optimize rAAV3 vectors to enhance liver tropism and use rAAV3 in combination with shikonin to treat liver disease

Mon Dec 01 00:00:00 UTC 2014

Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model.

Human gene therapy

Ling C,Wang Y,Zhang Y,Ejjigani A,Yin Z,Lu Y,Wang L,Wang M,Li J,Hu Z,Aslanidi GV,Zhong L,Gao G,Srivastava A,Ling C

PA1-988 was used in western blot to optimize rAAV3 vectors to enhance liver tropism and use rAAV3 in combination with shikonin to treat liver disease

Mon Dec 01 00:00:00 UTC 2014

Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration.

Neurobiology of disease

Ma M,Ferguson TA,Schoch KM,Li J,Qian Y,Shofer FS,Saatman KE,Neumar RW

PA1-988 was used in western blot to study Wallerian degeneration and the role of calpains in the cytoskeletal disintegration of axons

Thu Aug 01 00:00:00 UTC 2013

Calpastatin overexpression protects axonal transport in an in vivo model of traumatic axonal injury.

Journal of neurotrauma

Ma M,Shofer FS,Neumar RW

Published figure using GAPDH polyclonal antibody (Product # PA1-988) in Western Blot

Thu Nov 01 00:00:00 UTC 2012

The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes.

Molecular pharmacology

Gary-Bobo M,Elachouri G,Scatton B,Le Fur G,Oury-Donat F,Bensaid M

PA1-988 was used in western blot to study the effect of rimonabant on enzyme content of mouse 3T3 F442A preadipocytes

Wed Feb 01 00:00:00 UTC 2006

Bioinformatics

Protein Aliases: 38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; GAPDH; GAPDH-2; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; HGNC:4141; MGC88685; Peptidyl-cysteine S-nitrosylase GAPDH; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase

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Gene Aliases: BARS-38; CDABP0047; G3PD; GAPD; Gapd-s; GAPD2; GAPDH; GAPDH-2; GAPDH2; GAPDHS; GAPDS; HEL-S-162eP; HEL-S-278; HSD-35; HSD35; OK/SW-cl.12

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UniProt ID: (Human) P04406, (Human) O14556, (Mouse) P16858, (Rat) P04797, (Rat) Q9ESV6, (Mouse) Q64467

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Entrez Gene ID: (Human) 2597, (Dog) 403755, (Human) 26330, (Dog) 476483, (Mouse) 14433, (Rat) 24383, (Rat) 66020, (Mouse) 14447

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Function(s)

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity protein binding microtubule binding peptidyl-cysteine S-nitrosylase activity identical protein binding NADP binding NAD binding molecular_function oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Process(es)

gluconeogenesis spermatid development sperm motility positive regulation of glycolytic process canonical glycolysis glucose metabolic process glycolytic process oxidation-reduction process microtubule cytoskeleton organization regulation of macroautophagy negative regulation of translation peptidyl-cysteine S-trans-nitrosylation protein stabilization neuron apoptotic process cellular response to interferon-gamma carbohydrate metabolic process apoptotic process multicellular organism development response to ammonium ion regulation of translation

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GAPDH Polyclonal Antibody

GAPDH Antibody (PA1-988) in WB

Product Details

PA1-988

Western Blot (WB)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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