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GAS6 Antibody (PA5-47981) in IHC (P)
Immunohistochemical analysis of GAS6 in perfusion fixed paraffin-embedded sections of mouse intestine. Samples were incubated with GAS6 polyclonal antibody (Product # PA5-47981) using a dilution of 1 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen R... View More
Product Details
PA5-47981
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Gas6 Asp115-Pro673
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607376
Product Specific Information
In sandwich ELISAs, less than 10% cross-reactivity with recombinant human Gas6 is observed and less than 1% cross-reactivity with recombinant mouse Gas1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AXL receptor tyrosine kinase ligand; GAS 6; GAS-6; Growth arrest-specific protein 6
Gene Aliases: Gas-6; Gas6
UniProt ID: (Mouse) Q61592
Entrez Gene ID: (Mouse) 14456
phosphatidylserine binding
receptor binding
voltage-gated calcium channel activity
calcium ion binding
protein tyrosine kinase activator activity
receptor tyrosine kinase binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metal ion binding
receptor agonist activity
binding, bridging
neuron migration
positive regulation of protein phosphorylation
positive regulation of cytokine-mediated signaling pathway
positive regulation of glomerular filtration
protein phosphorylation
phagocytosis
signal transduction
enzyme linked receptor protein signaling pathway
blood coagulation
cellular response to starvation
positive regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
macrophage cytokine production
peptidyl-serine phosphorylation
fusion of virus membrane with host plasma membrane
viral genome replication
cell-substrate adhesion
positive regulation of TOR signaling
activation of protein kinase B activity
negative regulation of interferon-gamma production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein import into nucleus, translocation
regulation of ion transmembrane transport
cellular response to interferon-alpha
cellular response to drug
B cell chemotaxis
regulation of growth
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic cell clearance
negative regulation of sequence-specific DNA binding transcription factor activity
protein kinase B signaling
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
viral entry into host cell
receptor-mediated virion attachment to host cell
positive regulation of protein export from nucleus
positive regulation of fibroblast proliferation
negative regulation of interleukin-1 secretion
positive regulation of phagocytosis
positive regulation of protein kinase B signaling
positive regulation of protein tyrosine kinase activity
negative regulation of biomineral tissue development
positive regulation of ERK1 and ERK2 cascade
calcium ion transmembrane transport
cellular response to vitamin K
cellular response to glucose stimulus
cellular response to growth factor stimulus
protein targeting to plasma membrane
hematopoietic stem cell migration to bone marrow
negative regulation of oligodendrocyte apoptotic process
negative regulation of interleukin-6 secretion
negative regulation of fibroblast apoptotic process
positive regulation of receptor activity
negative regulation of endothelial cell apoptotic process
positive regulation of dendritic cell chemotaxis
negative regulation of dendritic cell apoptotic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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