Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 86%; Rat: 93%; Zebrafish: 79%
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Gene Aliases: RGD1305361
Entrez Gene ID: (Rat) 287631
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