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OriGene
GBA3 Monoclonal Antibody (OTI1C7), TrueMAB™
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FIGURE: 1 / 4
GBA3 Antibody (CF502604) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GBA3 (RC211035, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GBA3. Positive lysates LY402815 (100 µg) and LC402815 (20 µg) can be purchased separately from OriGene.
Product Details
CF502604
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1C7
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-150 and 370-469 of human GBA3 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; Cytosolic galactosylceramidase; Cytosolic GCase; Cytosolic glucosylceramidase; Cytosolic glycosylceramidase; Glucosidase beta acid 3; glucosidase, beta, acid 3 (cytosolic); Glucosylceramidase beta 3; Klotho-related protein; KLrP
Gene Aliases: CBG; CBGL1; GBA3; GLUC; KLRP
UniProt ID: (Human) Q9H227
Entrez Gene ID: (Human) 57733
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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