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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GBF1 Antibodies

          Bethyl Laboratories

          GBF1 Polyclonal Antibody

          View all (12) GBF1 antibodies

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          Cite GBF1 Polyclonal Antibody

          • Antibody Testing Data (2)
          GBF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          GBF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 2

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          GBF1 Antibody (IHC-00595) in IHC (P)

          Detection of mouse GBF1 by immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-GBF1 (Product # IHC-00595) used at a dilution of 1:250. Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GBF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GBF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          IHC-00595

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          1:100-1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1809 and 1859 of human golgi-specific brefeldin A resistance factor 1.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.0 to 8.0, with 0.1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Wet ice

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Based on 100% sequence identity, this antibody is predicted to react with Rat, Guinea pig_10141, Orangutan, Monkey, Chimpanzee, hirteen-lined ground squirrel, Small-eared galago and Chinese hamster

          Target Information

          This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BFA-resistant GEF 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

          View more View less

          Gene Aliases: 1700083E03Rik; AI035702; ARF1GEF; AW049900; GBF1; KIAA0248; mKIAA0248

          View more View less

          UniProt ID: (Human) Q92538, (Mouse) Q6DFZ1

          View more View less

          Entrez Gene ID: (Human) 8729, (Mouse) 107338

          View more View less

          Function(s)
          guanyl-nucleotide exchange factor activity ARF guanyl-nucleotide exchange factor activity protein binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-3,5-bisphosphate binding
          Process(es)
          cell activation involved in immune response ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER post-Golgi vesicle-mediated transport Golgi to endosome transport Golgi organization regulation of mitotic cell cycle protein transport viral process neutrophil chemotaxis regulation of ARF protein signal transduction protein localization to Golgi apparatus retrograde transport, endosome to Golgi positive regulation of GTPase activity COPI coating of Golgi vesicle establishment of monopolar cell polarity protein localization to endoplasmic reticulum exit site Golgi disassembly endoplasmic reticulum-Golgi intermediate compartment organization reactive oxygen species biosynthetic process protein localization to endoplasmic reticulum tubular network regulation of protein localization to cell surface regulation of cell adhesion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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