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Product Details
PA5-99627
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GBP4(Accession Q96PP9), corresponding to amino acid residues L556-R606.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818560
Product Specific Information
Antibody detects endogenous levels of total GBP4.
Target Information
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP.[supplied by OMIM, Dec 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GBP-4; GTP-binding protein 4; Guanine nucleotide-binding protein 4; guanylate binding protein 4; guanylate nucleotide binding protein 3; guanylate nucleotide binding protein 4; Guanylate-binding protein 4; guanylate-binding protein 4 homolog; macrophage activation 2
Gene Aliases: AW228052; Gbp3; GBP4; Mag-2; mKIAA4245; Mpa-2; Mpa2
UniProt ID: (Human) Q96PP9, (Mouse) A4UUI3
Entrez Gene ID: (Human) 115361, (Rat) 310917, (Mouse) 17472
metabolic process
cellular response to interferon-beta
defense response to protozoan
adhesion of symbiont to host
defense response to Gram-positive bacterium
cellular response to interferon-gamma
negative regulation of transcription from RNA polymerase II promoter
negative regulation of protein phosphorylation
negative regulation of protein ubiquitination
negative regulation of interferon-alpha production
negative regulation of protein import into nucleus
regulation of defense response to virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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