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Product Details
16317-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GCAT Fusion Protein Ag9367 (1-419 aa encoded by BC014457)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MWPGNAWRA ALFWVPRGRR AQSALAQLRG ILEGELEGIC GAGTWKSERV ITSRQGPHIR VDGVSGGILN FCANNYLGLS SHPEVIQAGL QALEEFGAGL SSVRFICGTQ SIHKNLEAKI ARFHQREDAI LYPSCYDANA GLFEALLTPE DAVLSDELNH ASIIDGIRLC KAHKYRYRHL DMADLEAKLQ EAQKHRLRLV ATDGAFSMDG DIAPLQEICC LASRYGALVF MDECHATGFL GPTGRGTDEL LGVMDQVTII NSTLGKALGG ASGGYTTGPG PLVSLLRQRA RPYLFSNSLP PAVVGCASKA LDLLMGSNTI VQSMAAKTQR FRSKMEAAGF TISGASHPIC PVMLGDARLA SRMADDMLKR GIFVIGFSYP VVPKGKAWIR VQISAVHSEE DIDRCVEAFV EVGRLHGALP (1-419 aa encoded by BC014457)
Target Information
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 2-amino-3-ketobutyrate-CoA ligase; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
Gene Aliases: AI526977; GCAT; KBL
UniProt ID: (Human) O75600, (Mouse) O88986
Entrez Gene ID: (Human) 23464, (Mouse) 26912, (Rat) 366959
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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