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Invitrogen
GCM1 Polyclonal Antibody
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Product Details
PA5-29438
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human GCM1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.84 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546914
Product Specific Information
Recommended positive controls: HepG2, HepG2 nucleus.
Predicted reactivity: Mouse (84%), Rat (84%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chorion-specific transcription factor GCMa; GCM motif protein 1; Glial cells missing homolog 1; hGCMa
Gene Aliases: GCM1; GCMA; hGCMa
UniProt ID: (Human) Q9NP62
Entrez Gene ID: (Human) 8521
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
zinc ion binding
histone deacetylase binding
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
anatomical structure morphogenesis
gliogenesis
positive regulation of transcription from RNA polymerase II promoter
calcium ion homeostasis
astrocyte fate commitment
positive regulation of syncytium formation by plasma membrane fusion
branching involved in labyrinthine layer morphogenesis
cell differentiation involved in embryonic placenta development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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