Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
GCNF Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
12712-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GCNF Fusion Protein Ag3395 (1-350 aa encoded by BC030600)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody specifically reacts with the 55 kDa NR6A1 protein.
Immunogen sequence: MERDEPPPS GGGGGGGSAG FLEPPAALPP PPRNGFCQDE LAELDPGTND RAEQRTCLIC GDRATGLHYG IISCEGCKGF FKRSICNKRV YRCSRDKNCV MSRKQRNRCQ YCRLLKCLQM GMNRKAIRED GMPGGRNKSI GPVQISEEEI ERIMSGQEFE EEANHWSNHG DSDHSSPGNR ASESNQPSPG STLSSRSVEL NGFMAFREQY MGMSVPPHYQ YIPHLFSYSG HSPLLPQQAR SLDPQSYSLI HQLLSAEDLE PLGTPMLIED GYAVTQAELF ALLCRLADEL LFRQIAWIKK LPFFCELSIK DYTCLLSSTW QELILLSSLT VYSKQIFGEL ADVTAKYSPS D (1-350 aa encoded by BC030600)
Target Information
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GCNF; Germ cell nuclear factor; germ cell nuclear factor variant 1; h hRTR; mGCNF; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR
Gene Aliases: 1700113M01Rik; CT150; GCNF; GCNF1; hGCNF; hRTR; NCNF; NR61; NR6A1; RTR
UniProt ID: (Human) Q8NHQ0, (Mouse) Q64249
Entrez Gene ID: (Human) 2649, (Rat) 362125, (Mouse) 14536
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
metal ion binding
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
gamete generation
spermatogenesis
cell proliferation
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
steroid hormone mediated signaling pathway
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support