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Invitrogen
GCP2 Polyclonal Antibody
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FIGURE: 1 / 4
GCP2 Antibody (PA5-21433) in ICC/IF
GCP2 Polyclonal Antibody detects TUBGCP2 protein at centrosome by confocal immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: TUBGCP2 protein stained by GCP2 Polyclonal Antibody (Product # PA5-21433) diluted at 1:500. Blue: Hoechst 33342 staining.[Images captured by Olympus FV10i Confocal Laser Scanning Microscope].
Product Details
PA5-21433
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human GCP2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154079
Product Specific Information
Recommended positive controls: A431, HeLa, NIH-3T3.
Predicted reactivity: Mouse (88%), Rat (88%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The γ-Tubulin complex is composed of γ Tubulin and the γ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. γ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubulin complex. GCP2 (γ-Tubulin complex component 2), also known as TUBGCP2 or SPBC97 (spindle pole body protein Spc97 homolog) is a ubiquitously expressed 902 amino acid protein that localizes to the centrosome and is involved in microtubule nucleation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gamma-ring complex protein 103 kDa; Gamma-tubulin complex component 2; GCP-2; h103p; hGrip103; hSpc97; Spindle pole body protein Spc97 homolog; tubulin, gamma complex associated protein 2
Gene Aliases: 1700022B05Rik; GCP-2; GCP2; Grip103; h103p; hGCP2; hSpc97; SPBC97; Spc97p; TUBGCP2
UniProt ID: (Human) Q9BSJ2, (Mouse) Q921G8
Entrez Gene ID: (Human) 10844, (Mouse) 74237
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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