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Product Details
66371-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1B7D12
Immunogen
GDF10 Fusion Protein Ag4906 (1-288 aa encoded by BC028237)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALAPPPRG LWQAKDISPI VKAARRDGEL LLSAQLDSEE RDPGVPRPSP YAPYILVYAN DLAISEPNSV AVTLQRYDPF PAGDPEPRAA PNNSADPRVR RAAQATGPLQ DNELPGLDER PPRAHAQHFH KHQLWPSPFR ALKPRPGRKD RRKKGQEVFM AASQVLDFDE KTMQKARRKQ WDEPRVCSRR YLKVDFADIG WNEWIISPKS FDAYYCAGAC EFPMPKIVRP SNHATIQSIV RAVGIIPGIP EPCCVPDKMN SLGVLFLDEN RNVVLKVYPN MSVDTCACR (1-288 aa encoded by BC028237 )
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BIP; BMP-3B; Bone morphogenetic protein 3B; Bone-inducing protein; GDF-10; Growth/differentiation factor 10; prepro bone inducing protein
Gene Aliases: BMP-3b; BMP3B; GDF10
UniProt ID: (Human) P55107, (Rat) P55108
Entrez Gene ID: (Human) 2662, (Rat) 79216
skeletal system development
osteoblast differentiation
transforming growth factor beta receptor signaling pathway
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
fat cell differentiation
negative regulation of osteoblast differentiation
cell development
SMAD protein signal transduction
cerebellum development
regulation of ossification
ovulation cycle
positive regulation of osteoblast differentiation
response to transforming growth factor beta
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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