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Product Details
BS-9845R-A680
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GDN/SERPINE2
Conjugate
Excitation/Emission Max
681/704 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; Glia-derived nexin/protease nexin I; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; plasminogen activator inhibitor type 1; PN-1; Protease nexin 1; Protease nexin I; protease nexin PN-1; serine (or cysteine) peptidase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serpin peptidase inhibitor, clade E, member 2; SERPINE 2
Gene Aliases: B230326M24Rik; GDN; GDNPF; Gdnpn1; PAI-1; PI-7; PI7; PN-1; PN1; PNI; SERPINE2; Spi4; Spin4
UniProt ID: (Human) P07093, (Rat) P07092, (Mouse) Q07235
Entrez Gene ID: (Human) 5270, (Rat) 29366, (Mouse) 20720
embryo implantation
blood coagulation
negative regulation of cell proliferation
response to radiation
response to wounding
negative regulation of peptidase activity
negative regulation of platelet activation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
negative regulation of blood coagulation
negative regulation of cell growth
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
negative regulation of protein processing
regulation of cell migration
multicellular organism development
nervous system development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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