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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GFAP Antibodies

          Proteintech

          GFAP Polyclonal Antibody

          466 References
          View all (235) GFAP antibodies

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          Datasheet
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          Cite GFAP Polyclonal Antibody

          • Antibody Testing Data (19)
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          GFAP Antibody (16825-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded Hippocampus tissue slide from Alzheimer Mouse Model using 16825-1-AP (GFAP antibody) at dilution of 1:50000 (under 10x lens). Data from NeuroScience Associates, Inc. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GFAP Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          GFAP Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          GFAP Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          GFAP Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          GFAP Antibody in Western Blot (WB)
          GFAP Antibody in Western Blot (WB)
          GFAP Antibody in Western Blot (WB)
          GFAP Antibody in Western Blot (WB)

          Product Details

          16825-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:5,000-1:50,000
          View 110 publications 110 publications

          Immunohistochemistry (IHC)

          -
          View 64 publications 64 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:2000
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 253 publications 253 publications

          Miscellaneous PubMed (MISC)

          -
          View 15 publications 15 publications

          Not applicable (N/A)

          -
          View 24 publications 24 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Hamster, Human, Mouse, Pig, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          GFAP Fusion Protein Ag10423 (83-432 aa encoded by BC013596)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.43 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: YIEKVRFLE QQNKALAAEL NQLRAKEPTK LADVYQAELR ELRLRLDQLT ANSARLEVER DNLAQDLATV RQKLQDETNL RLEAENNLAA YRQEADEATL ARLDLERKIE SLEEEIRFLR KIHEEEVREL QEQLARQQVH VELDVAKPDL TAALKEIRTQ YEAMASSNMH EAEEWYRSKF ADLTDAAARN AELLRQAKHE ANDYRRQLQS LTCDLESLRG TNESLERQMR EQEERHVREA ASYQEALARL EEEGQSLKDE MARHLQEYQD LLNVKLALDI EIATYRKLLE GEENRITIPV QTFSNLQIRE TSLDTKSVSE GHLKRNIVVK TVEMRDGEVI KESKQEHKDV M (83-432 aa encoded by BC013596)

          Target Information

          GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Astrocyte or Intermediate Filament Protein; FLJ45472; GFAP; GFAP epsilon; Glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; intermediate filament; intermediate filament protein

          View more View less

          Gene Aliases: AI836096; ALXDRD; GFAP

          View more View less

          UniProt ID: (Human) P14136, (Rat) P47819, (Mouse) P03995

          View more View less

          Entrez Gene ID: (Human) 2670, (Rat) 24387, (Mouse) 14580

          View more View less

          Function(s)
          glycoprotein binding integrin binding structural constituent of cytoskeleton protein binding kinase binding structural molecule activity
          Process(es)
          response to wounding positive regulation of Schwann cell proliferation negative regulation of neuron projection development astrocyte development extracellular matrix organization neuron projection regeneration intermediate filament-based process intermediate filament organization regulation of neurotransmitter uptake Bergmann glial cell differentiation positive regulation of glial cell proliferation long-term synaptic potentiation regulation of protein complex assembly regulation of chaperone-mediated autophagy
          It has to be done as per old AB suggested Products section.
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