Product References
Transfusion with Blood Plasma from Young Mice Affects rTg4510 Transgenic Tau Mice Modeling of Alzheimer's Disease.
Brain sciences
Hernandez CM,Barkey RE,Craven KM,Pedemonte KA,Alisantosa B,Sanchez JO,Flinn JM
MA5-12023 was used in Western Blot to find that Tau mice injected with plasma had lower expression of phosphorylated tau (ptau) in the brain, accompanied by fewer tau tangles in the cortex and CA1 region of the hippocampus and smaller tau tangles in the cortex, when compared to Tau mice injected with saline.
Tue May 23 00:00:00 UTC 2023
Transfusion with Blood Plasma from Young Mice Affects rTg4510 Transgenic Tau Mice Modeling of Alzheimer's Disease.
Brain sciences
Hernandez CM,Barkey RE,Craven KM,Pedemonte KA,Alisantosa B,Sanchez JO,Flinn JM
MA5-12023 was used in Western Blot to find that Tau mice injected with plasma had lower expression of phosphorylated tau (ptau) in the brain, accompanied by fewer tau tangles in the cortex and CA1 region of the hippocampus and smaller tau tangles in the cortex, when compared to Tau mice injected with saline.
Tue May 23 00:00:00 UTC 2023
Low-Field Magnetic Stimulation Alleviates MPTP-Induced Alterations in Motor Function and Dopaminergic Neurons in Male Mice.
International journal of molecular sciences
Sekar S,Zhang Y,Miranzadeh Mahabadi H,Buettner B,Taghibiglou C
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Western Blot
Mon Jun 19 00:00:00 UTC 2023
Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury.
Biomaterials research
Kim SJ,Ko WK,Han GH,Lee D,Cho MJ,Sheen SH,Sohn S
MA5-12023 was used in Immunohistochemistry to demonstrate the important role of Sema3A in NSC transplantation therapy, which may be considered as a future cell transplantation therapy for SCI cases.
Sun Oct 15 00:00:00 UTC 2023
Axon guidance gene-targeted siRNA delivery system improves neural stem cell transplantation therapy after spinal cord injury.
Biomaterials research
Kim SJ,Ko WK,Han GH,Lee D,Cho MJ,Sheen SH,Sohn S
MA5-12023 was used in Immunohistochemistry to demonstrate the important role of Sema3A in NSC transplantation therapy, which may be considered as a future cell transplantation therapy for SCI cases.
Sun Oct 15 00:00:00 UTC 2023
Single-cell analysis reveals inflammatory interactions driving macular degeneration.
Nature communications
Kuchroo M,DiStasio M,Song E,Calapkulu E,Zhang L,Ige M,Sheth AH,Majdoubi A,Menon M,Tong A,Godavarthi A,Xing Y,Gigante S,Steach H,Huang J,Huguet G,Narain J,You K,Mourgkos G,Dhodapkar RM,Hirn MJ,Rieck B,Wolf G,Krishnaswamy S,Hafler BP
MA5-12023 was used in Immunohistochemistry to identify a microglia-to-astrocyte signaling axis mediated by interleukin-1β which drives angiogenesis characteristic of disease pathogenesis.
Fri May 05 00:00:00 UTC 2023
Short exposure to photo-oxidative damage triggers molecular signals indicative of early retinal degeneration.
Frontiers in immunology
Wooff Y,Cioanca AV,Wills E,Chu-Tan JA,Sekar R,Natoli R
MA5-12023 was used in Immunohistochemistry to determine if short exposure to photo-oxidative damage could be used to induce early retinal molecular changes and advance this as a potential model for studying early-stage age-related macular degeneration (AMD).
Tue May 16 00:00:00 UTC 2023
Neurogenesis Is Reduced at 48 h in the Subventricular Zone Independent of Cell Death in a Piglet Model of Perinatal Hypoxia-Ischemia.
Frontiers in pediatrics
Alonso-Alconada D,Gressens P,Golay X,Robertson NJ
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Immunohistochemistry
Wed Dec 11 00:00:00 UTC 2024
Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
International journal of molecular sciences
Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R
MA5-12023 was used in Immunohistochemistry to investigate a pathogenic role for epigenetics and other biomarkers in the male APP/BIN1/COPS5 triple-transgenic (3xTg) mouse model of Alzheimer's Disease.
Wed Feb 23 00:00:00 UTC 2022
Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
International journal of molecular sciences
Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R
MA5-12023 was used in Immunohistochemistry to investigate a pathogenic role for epigenetics and other biomarkers in the male APP/BIN1/COPS5 triple-transgenic (3xTg) mouse model of Alzheimer's Disease.
Wed Feb 23 00:00:00 UTC 2022
Astrocyte-specific loss of lactoferrin influences neuronal structure and function by interfering with cholesterol synthesis.
Glia
Xu SF,Pang ZQ,Fan YG,Zhang YH,Meng YH,Bai CY,Jia MY,Chen YH,Wang ZY,Guo C
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that astrocytic lactoferrin (Lf) might directly or indirectly control in situ cholesterol synthesis, which may be implicated in neurodevelopment and several neurological diseases.
Thu Dec 01 00:00:00 UTC 2022
Astrocyte-specific loss of lactoferrin influences neuronal structure and function by interfering with cholesterol synthesis.
Glia
Xu SF,Pang ZQ,Fan YG,Zhang YH,Meng YH,Bai CY,Jia MY,Chen YH,Wang ZY,Guo C
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that astrocytic lactoferrin (Lf) might directly or indirectly control in situ cholesterol synthesis, which may be implicated in neurodevelopment and several neurological diseases.
Thu Dec 01 00:00:00 UTC 2022
Astrocyte-specific loss of lactoferrin influences neuronal structure and function by interfering with cholesterol synthesis.
Glia
Xu SF,Pang ZQ,Fan YG,Zhang YH,Meng YH,Bai CY,Jia MY,Chen YH,Wang ZY,Guo C
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that astrocytic lactoferrin (Lf) might directly or indirectly control in situ cholesterol synthesis, which may be implicated in neurodevelopment and several neurological diseases.
Thu Dec 01 00:00:00 UTC 2022
Micropatterned Neurovascular Interface to Mimic the Blood-Brain Barrier's Neurophysiology and Micromechanical Function: A BBB-on-CHIP Model.
Cells
Singh AV,Chandrasekar V,Laux P,Luch A,Dakua SP,Zamboni P,Shelar A,Yang Y,Pandit V,Tisato V,Gemmati D
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Immunocytochemistry
Thu Sep 08 00:00:00 UTC 2022
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Cancer discovery
Panditharatna E,Marques JG,Wang T,Trissal MC,Liu I,Jiang L,Beck A,Groves A,Dharia NV,Li D,Hoffman SE,Kugener G,Shaw ML,Mire HM,Hack OA,Dempster JM,Lareau C,Dai L,Sigua LH,Quezada MA,Stanton AJ,Wyatt M,Kalani Z,Goodale A,Vazquez F,Piccioni F,Doench JG,Root DE,Anastas JN,Jones KL,Conway AS,Stopka S,Regan MS,Liang Y,Seo HS,Song K,Bashyal P,Jerome WP,Mathewson ND,Dhe-Paganon S,Suvà ML,Carcaboso AM,Lavarino C,Mora J,Nguyen QD,Ligon KL,Shi Y,Agnihotri S,Agar NYR,Stegmaier K,Stiles CD,Monje M,Golub TR,Qi J,Filbin MG
MA5-12023 was used in Immunohistochemistry-immunofluorescence to identify the BRG1-BAF complex as a critical regulator of enhancer and transcription factor landscapes, which maintain H3K27M glioma in their progenitor state, precluding glial differentiation, and establish pharmacologic targeting of the BAF complex as a novel treatment strategy for pediatric H3K27M glioma.
Fri Dec 02 00:00:00 UTC 2022
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Cancer discovery
Panditharatna E,Marques JG,Wang T,Trissal MC,Liu I,Jiang L,Beck A,Groves A,Dharia NV,Li D,Hoffman SE,Kugener G,Shaw ML,Mire HM,Hack OA,Dempster JM,Lareau C,Dai L,Sigua LH,Quezada MA,Stanton AJ,Wyatt M,Kalani Z,Goodale A,Vazquez F,Piccioni F,Doench JG,Root DE,Anastas JN,Jones KL,Conway AS,Stopka S,Regan MS,Liang Y,Seo HS,Song K,Bashyal P,Jerome WP,Mathewson ND,Dhe-Paganon S,Suvà ML,Carcaboso AM,Lavarino C,Mora J,Nguyen QD,Ligon KL,Shi Y,Agnihotri S,Agar NYR,Stegmaier K,Stiles CD,Monje M,Golub TR,Qi J,Filbin MG
MA5-12023 was used in Immunohistochemistry-immunofluorescence to identify the BRG1-BAF complex as a critical regulator of enhancer and transcription factor landscapes, which maintain H3K27M glioma in their progenitor state, precluding glial differentiation, and establish pharmacologic targeting of the BAF complex as a novel treatment strategy for pediatric H3K27M glioma.
Fri Dec 02 00:00:00 UTC 2022
Parabrachial nucleus astrocytes regulate wakefulness and isoflurane anesthesia in mice.
Frontiers in pharmacology
Liu PC,Yao W,Chen XY,Su WK,Zheng ZH,Yan XB,Deng YL,Shi KG,Liu X,Gao YW,Lin TT,Zhu YX,Lin YX,Zhu ZH,Cai P,Zhang LC,Chen L
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to show that PBN astrocytes are a key neural substrate regulating wakefulness and emergence from isoflurane anesthesia.
Thu Feb 02 00:00:00 UTC 2023
A steroid receptor coactivator small molecule "stimulator" attenuates post-stroke ischemic brain injury.
Frontiers in molecular neuroscience
McClendon LK,Garcia RL,Lazaro T,Robledo A,Vasandani V,Luna ZAE,Rao AS,Srivatsan A,Lonard DM,Dacso CC,Kan P,O'Malley BW
MA5-12023 was used in Immunohistochemistry to investigate if an MCB-613 derivative (MCB-10-1), could protect the brain following ischemic injury.
Thu Dec 22 00:00:00 UTC 2022
Astrocytes modulate extracellular neurotransmitter levels and excitatory neurotransmission in dorsolateral striatum via dopamine D2 receptor signaling.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Adermark L,Lagström O,Loftén A,Licheri V,Havenäng A,Loi EA,Stomberg R,Söderpalm B,Domi A,Ericson M
MA5-12023 was used in Immunohistochemistry to support a role for astrocytes in modulating striatal neurotransmission and suggest that reduced transmission after astrocytic inhibition involves dopamine.
Fri Jul 01 00:00:00 UTC 2022
Sex-Dependent Effects of Chronic Microdrive Implantation on Acquisition of Trace Eyeblink Conditioning.
Neurobiology of learning and memory
Rapp AP,Hark TJ,Power JM,Savas JN,Matthew Oh M,Disterhoft JF
MA5-12023 was used in Western Blotting to suggest that significant alterations in the MAPK pathway, acute inflammation, and brain derived neurotrophic factor may underlie observed sex- and surgery-dependent effects on learning.
Thu Sep 01 00:00:00 UTC 2022
Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early.
Frontiers in oncology
Morelli M,Lessi F,Barachini S,Liotti R,Montemurro N,Perrini P,Santonocito OS,Gambacciani C,Snuderl M,Pieri F,Aquila F,Farnesi A,Naccarato AG,Viacava P,Cardarelli F,Ferri G,Mulholland P,Ottaviani D,Paiar F,Liberti G,Pasqualetti F,Menicagli M,Aretini P,Signore G,Franceschi S,Mazzanti CM
MA5-12023 was used in Immunohistochemistry to develop a novel functional precision medicine approach to test the response to anticancer treatments in organoids derived from the resected tumors of glioblastoma patients.
Sat Sep 24 00:00:00 UTC 2022
Immunofluorescent Evidence for Nuclear Localization of Aromatase in Astrocytes in the Rat Central Nervous System.
International journal of molecular sciences
Kata D,Gróf I,Hoyk Z,Ducza E,Deli MA,Zupkó I,Földesi I
MA5-12023 was used in Immunocytochemistry to suggest a new unique mechanism in astrocytes that may regulate certain CNS functions via estradiol production.
Thu Aug 11 00:00:00 UTC 2022
The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids.
Cell proliferation
Kim HM,Lee SH,Lim J,Yoo J,Hwang DY
MA5-12023 was used in Immunohistochemistry to identify that epidermal growth factor receptor variant type III mutation induced astrogenesis and massive cell proliferation in a human brain development model.
Mon Feb 01 00:00:00 UTC 2021
Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells.
Frontiers in molecular neuroscience
Francistiová L,Vörös K,Lovász Z,Dinnyés A,Kobolák J
MA5-12023 was used in Immunocytochemistry to show P2X7 receptor, which is involved in neurodegenerative diseases, to be expressed on human hiPSC-derived microglia-like cells, hiPSC-derived neuronal progenitors and hiPSC-derived matured neuronal cells.
Fri Apr 05 00:00:00 UTC 2024
Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells.
Frontiers in molecular neuroscience
Francistiová L,Vörös K,Lovász Z,Dinnyés A,Kobolák J
MA5-12023 was used in Immunocytochemistry to show P2X7 receptor, which is involved in neurodegenerative diseases, to be expressed on human hiPSC-derived microglia-like cells, hiPSC-derived neuronal progenitors and hiPSC-derived matured neuronal cells.
Fri Apr 05 00:00:00 UTC 2024
Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells.
Frontiers in molecular neuroscience
Francistiová L,Vörös K,Lovász Z,Dinnyés A,Kobolák J
MA5-12023 was used in Immunocytochemistry to show P2X7 receptor, which is involved in neurodegenerative diseases, to be expressed on human hiPSC-derived microglia-like cells, hiPSC-derived neuronal progenitors and hiPSC-derived matured neuronal cells.
Fri Apr 05 00:00:00 UTC 2024
Phenotypic and functional comparison of rat enteric neural crest-derived cells during fetal and early-postnatal stages.
Neural regeneration research
Tian DH,Qin CH,Xu WY,Pan WK,Zhao YY,Zheng BJ,Chen XL,Liu Y,Gao Y,Yu H
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry to show that, compared with postnatal enteric neural crest-derived cells (ENCCs), fetal ENCCs exhibit higher survival, proliferation, and migration abilities.
Mon Nov 01 00:00:00 UTC 2021
Phenotypic and functional comparison of rat enteric neural crest-derived cells during fetal and early-postnatal stages.
Neural regeneration research
Tian DH,Qin CH,Xu WY,Pan WK,Zhao YY,Zheng BJ,Chen XL,Liu Y,Gao Y,Yu H
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry to show that, compared with postnatal enteric neural crest-derived cells (ENCCs), fetal ENCCs exhibit higher survival, proliferation, and migration abilities.
Mon Nov 01 00:00:00 UTC 2021
Ultrarapid Inflammation of the Olfactory Bulb After Spinal Cord Injury: Protective Effects of the Granulocyte Colony-Stimulating Factor on Early Neurodegeneration in the Brain.
Frontiers in aging neuroscience
Lin MS,Chiu IH,Lin CC
MA5-12023 was used in Western Blot, Immunohistochemistry to provide a basis for future studies on pathological mechanisms of early neurodegenerative diseases involving the olfactory bulb and enable early clinical drug intervention.
Tue Jul 13 00:00:00 UTC 2021
Ultrarapid Inflammation of the Olfactory Bulb After Spinal Cord Injury: Protective Effects of the Granulocyte Colony-Stimulating Factor on Early Neurodegeneration in the Brain.
Frontiers in aging neuroscience
Lin MS,Chiu IH,Lin CC
MA5-12023 was used in Western Blot, Immunohistochemistry to provide a basis for future studies on pathological mechanisms of early neurodegenerative diseases involving the olfactory bulb and enable early clinical drug intervention.
Tue Jul 13 00:00:00 UTC 2021
Ultrarapid Inflammation of the Olfactory Bulb After Spinal Cord Injury: Protective Effects of the Granulocyte Colony-Stimulating Factor on Early Neurodegeneration in the Brain.
Frontiers in aging neuroscience
Lin MS,Chiu IH,Lin CC
MA5-12023 was used in Western Blot, Immunohistochemistry to provide a basis for future studies on pathological mechanisms of early neurodegenerative diseases involving the olfactory bulb and enable early clinical drug intervention.
Tue Jul 13 00:00:00 UTC 2021
Ultrarapid Inflammation of the Olfactory Bulb After Spinal Cord Injury: Protective Effects of the Granulocyte Colony-Stimulating Factor on Early Neurodegeneration in the Brain.
Frontiers in aging neuroscience
Lin MS,Chiu IH,Lin CC
MA5-12023 was used in Western Blot, Immunohistochemistry to provide a basis for future studies on pathological mechanisms of early neurodegenerative diseases involving the olfactory bulb and enable early clinical drug intervention.
Tue Jul 13 00:00:00 UTC 2021
Decellularized spinal cord meninges extracellular matrix hydrogel that supports neurogenic differentiation and vascular structure formation.
Journal of tissue engineering and regenerative medicine
Ozudogru E,Isik M,Eylem CC,Nemutlu E,Arslan YE,Derkus B
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Immunohistochemistry
Mon Nov 01 00:00:00 UTC 2021
SIX1/EYA1 are novel liver damage biomarkers in chronic hepatitis B and other liver diseases.
Annals of translational medicine
Xu B,Yang Q,Tang Y,Tan Z,Fu H,Peng J,Xiang X,Gan L,Deng G,Mao Q,Xu PX,Jiang Y,Ding J
MA5-12023 was used in Immunohistochemistry to conclude that SIX1 and EYA1 are novel biomarkers of liver damage in patients of CHB and other liver diseases, with potential clinical utility.
Tue Jun 01 00:00:00 UTC 2021
A Noradrenergic Lesion Attenuates Surgery-Induced Cognitive Impairment in Rats by Suppressing Neuroinflammation.
Frontiers in molecular neuroscience
Wang J,Zhou Y,Li K,Li X,Guo M,Peng M
MA5-12023 was used in Immunohistochemistry-immunofluorescence to provide evidence of the effects of LCNE in modulating neuroinflammation in rats with POCD and provide a new perspective in the prevention and treatment of POCD.
Sat Dec 18 00:00:00 UTC 2021
Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro.
Molecular therapy oncolytics
Aslam N,Abusharieh E,Abuarqoub D,Ali D,Al-Hattab D,Wehaibi S,Al-Kurdi B,Jamali F,Alshaer W,Jafar H,Awidi AS
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to conclude that different types of mesenchymal stem cells possess antitumor properties and their paracrine factors, in combination with anti-immune modalities, can provide practical therapeutic targets for glioblastoma treatment.
Fri Mar 26 00:00:00 UTC 2021
Astrocytes Exhibit a Protective Role in Neuronal Firing Patterns under Chemically Induced Seizures in Neuron-Astrocyte Co-Cultures.
International journal of molecular sciences
Ahtiainen A,Genocchi B,Tanskanen JMA,Barros MT,Hyttinen JAK,Lenk K
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to assess the modulatory roles of astrocytes during epileptic-like conditions and in compensating drug-elicited hyperactivity.
Thu Nov 25 00:00:00 UTC 2021
Direct Cell Reprogramming of Mouse Fibroblasts into Functional Astrocytes Using Lentiviral Overexpression of the Transcription Factors NFIA, NFIB, and SOX9.
Methods in molecular biology (Clifton, N.J.)
Qiu B,de Vries RJ,Caiazzo M
MA5-12023 was used in Immunocytochemistry to generate iAstrocytes starting from skin fibroblasts and this approach can be adapted for a wide range of somatic cell types.
Tue Aug 31 00:00:00 UTC 2021
Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes.
PLoS pathogens
Qiao H,Guo M,Shang J,Zhao W,Wang Z,Liu N,Li B,Zhou Y,Wu Y,Chen P
MA5-12023 was used in Immunohistochemistry-immunofluorescence to study fetal brain development and the potential neuropathological effects induced by the HSV-1 infections.
Thu Oct 01 00:00:00 UTC 2020
Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes.
PLoS pathogens
Qiao H,Guo M,Shang J,Zhao W,Wang Z,Liu N,Li B,Zhou Y,Wu Y,Chen P
MA5-12023 was used in Immunohistochemistry-immunofluorescence to study fetal brain development and the potential neuropathological effects induced by the HSV-1 infections.
Thu Oct 01 00:00:00 UTC 2020
Isolation and characterization of human optic nerve head astrocytes and lamina cribrosa cells.
Experimental eye research
Lopez NN,Clark AF,Tovar-Vidales T
MA5-12023 was used in Immunocytochemistry to provide a technique to better understand the molecular and cell-specific changes in glaucomatous damage to the ONH.
Sat Aug 01 00:00:00 UTC 2020
Isolation and characterization of human optic nerve head astrocytes and lamina cribrosa cells.
Experimental eye research
Lopez NN,Clark AF,Tovar-Vidales T
MA5-12023 was used in Immunocytochemistry to provide a technique to better understand the molecular and cell-specific changes in glaucomatous damage to the ONH.
Sat Aug 01 00:00:00 UTC 2020
Specific Frequency Electroacupuncture Stimulation Transiently Enhances the Permeability of the Blood-Brain Barrier and Induces Tight Junction Changes.
Frontiers in neuroscience
Zhang S,Gong P,Zhang J,Mao X,Zhao Y,Wang H,Gan L,Lin X
MA5-12023 was used in Western Blotting to propose that specific frequency EA can transiently open the BBB and may be related to the change of tight junctions (TJ).
Sat Oct 31 00:00:00 UTC 2020
Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.
Nature communications
Xu ZX,Kim GH,Tan JW,Riso AE,Sun Y,Xu EY,Liao GY,Xu H,Lee SH,Do NY,Lee CH,Clipperton-Allen AE,Kwon S,Page DT,Lee KJ,Xu B
MA5-12023 was used in Western Blotting to propose that functional perturbation of male microglia is an important cause for sex-biased autism spectrum disorders (ASD).
Tue Apr 14 00:00:00 UTC 2020
The effects of ozone exposure and sedentary lifestyle on neuronal microglia and mitochondrial bioenergetics of female Long-Evans rats.
Toxicology and applied pharmacology
Valdez M,Valdez JM,Freeborn D,Johnstone AFM,Kodavanti PRS
MA5-12023 was used in Immunohistochemistry to demonstrate that Ozone (O3) induces microglia reactivity within stress centers of the brain and that mitochondrial bioenergetics are altered.
Tue Dec 01 00:00:00 UTC 2020
Astrocytes shape the plastic response of adult cortical neurons to vision loss.
Glia
Hennes M,Lombaert N,Wahis J,Van den Haute C,Holt MG,Arckens L
MA5-12023 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to highlight an integral role for astrocytes in mediating adult cortical plasticity and unmask astrocyte specific Gi signaling as an interesting therapeutic pathway for brain plasticity regulation.
Thu Oct 01 00:00:00 UTC 2020
Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study.
PloS one
De Meulenaere V,Bonte E,Verhoeven J,Kalala Okito JP,Pieters L,Vral A,De Wever O,Leybaert L,Goethals I,Vanhove C,Descamps B,Deblaere K
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Immunohistochemistry
Thu Mar 19 00:00:00 UTC 2020
Morphine immunomodulation prolongs inflammatory and postoperative pain while the novel analgesic ZH853 accelerates recovery and protects against latent sensitization.
Journal of neuroinflammation
Feehan AK,Zadina JE
MA5-12023 was used in Immunohistochemistry to determine if endomorphin analog ZH853's lack of interaction with the neuroimmune system can reduce the risk of prolonged pain.
Tue May 21 00:00:00 UTC 2019
Mitochondrial Bioenergetics in Brain Following Ozone Exposure in Rats Maintained on Coconut, Fish and Olive Oil-Rich Diets.
International journal of molecular sciences
Valdez MC,Freeborn D,Valdez JM,Johnstone AFM,Snow SJ,Tennant AH,Kodavanti UP,Kodavanti PRS
MA5-12023 was used in Immunohistochemistry to show that acute ozone exposure alters mitochondrial bioenergetics in rats and co-treatments with fatty acids alleviate some of the adverse effects within the brain.
Fri Dec 13 00:00:00 UTC 2019
A Single Primary Blast-Induced Traumatic Brain Injury in a Rodent Model Causes Cell-Type Dependent Increase in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Isoforms in Vulnerable Brain Regions.
Journal of neurotrauma
Rama Rao KV,Iring S,Younger D,Kuriakose M,Skotak M,Alay E,Gupta RK,Chandra N
MA5-12023 was used in Immunohistochemistry-immunofluorescence to examine the expression of NOX1 and NOX2, the corresponding superoxide production, and the extent of lipid peroxidation adducts of 4-hydroxynonenal to a range of proteins following traumatic brain injury.
Sat Sep 01 00:00:00 UTC 2018
Histopathological changes in the choroid plexus after traumatic brain injury in the rats: a histologic and immunohistochemical study.
Folia morphologica
Özevren H,Deveci E,Tuncer MC
MA5-12023 was used in Immunohistochemistry to analyse the histopathological changes in E-cadherin and vascular endothelial growth factor expression after TBI in rats.
Wed Aug 14 00:00:00 UTC 2019
Neurotoxic reactive astrocytes are induced by activated microglia.
Nature
Liddelow SA,Guttenplan KA,Clarke LE,Bennett FC,Bohlen CJ,Schirmer L,Bennett ML,Münch AE,Chung WS,Peterson TC,Wilton DK,Frouin A,Napier BA,Panicker N,Kumar M,Buckwalter MS,Rowitch DH,Dawson VL,Dawson TM,Stevens B,Barres BA
MA5-12023 was used in immunohistochemistry - frozen section to identify an astrocyte subtype induced by activated microglia
Thu Jan 26 00:00:00 UTC 2017
Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury.
Glia
Shiow LR,Favrais G,Schirmer L,Schang AL,Cipriani S,Andres C,Wright JN,Nobuta H,Fleiss B,Gressens P,Rowitch DH
MA5-12023 was used in Immunohistochemistry-immunofluorescence to investigate the downstream effects of pro-inflammatory IL-1Β to induce cyclooxygenase-2 and prostaglandin E2 production in white matter.
Fri Dec 01 00:00:00 UTC 2017
Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury.
Glia
Shiow LR,Favrais G,Schirmer L,Schang AL,Cipriani S,Andres C,Wright JN,Nobuta H,Fleiss B,Gressens P,Rowitch DH
MA5-12023 was used in Immunohistochemistry-immunofluorescence to investigate the downstream effects of pro-inflammatory IL-1Β to induce cyclooxygenase-2 and prostaglandin E2 production in white matter.
Fri Dec 01 00:00:00 UTC 2017
Interleukin-1β secreted from betanodavirus-infected microglia caused the death of neurons in giant grouper brains.
Developmental and comparative immunology
Chiang YH,Wu YC,Chi SC
MA512023 was used in immunocytochemistry to study neuronal death caused by nervous necrosis virus infection
Mon May 01 00:00:00 UTC 2017
Recurrent intracranial neurenteric cyst with malignant transformation: A case report and literature review.
Oncology letters
Yang Y,Fang J,Li DA,Wang L,Ji N,Zhang J
MA5-12023 was used in immunohistochemistry - paraffin section to study a case report and literature review of recurrent intracranial neurenteric cyst with malignant transformation
Sun May 01 00:00:00 UTC 2016
Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling.
Scientific reports
Liu S,Li Q,Zhang MT,Mao-Ying QL,Hu LY,Wu GC,Mi WL,Wang YQ
MA5-12023 was used in immunohistochemistry to study the amelioration of neuropathic pain by down-regulating spinal IL-1-beta via suppressing JAK2-STAT3 signaling and astroglial NALP1 inflammasome by curcumin
Wed Jul 06 00:00:00 UTC 2016
Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke.
PloS one
Hochmeister S,Engel O,Adzemovic MZ,Pekar T,Kendlbacher P,Zeitelhofer M,Haindl M,Meisel A,Fazekas F,Seifert-Held T
MA5-12023 was used in immunohistochemistry - paraffin section measure LCN2 in ischemic samples
Mon Jul 17 00:00:00 UTC 2017
Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice.
Anesthesiology
Liu S,Mi WL,Li Q,Zhang MT,Han P,Hu S,Mao-Ying QL,Wang YQ
MA5-12023 was used in immunohistochemistry - frozen section and western blot to determine the correlation between neuronal caMKII-CREB and astroglial JAK2-STAT3 cascades in mice and how spinal IL-33/ST2 signaling contributes to neuropathic pain
Sun Nov 01 00:00:00 UTC 2015
Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice.
Anesthesiology
Liu S,Mi WL,Li Q,Zhang MT,Han P,Hu S,Mao-Ying QL,Wang YQ
MA5-12023 was used in immunohistochemistry - frozen section and western blot to determine the correlation between neuronal caMKII-CREB and astroglial JAK2-STAT3 cascades in mice and how spinal IL-33/ST2 signaling contributes to neuropathic pain
Sun Nov 01 00:00:00 UTC 2015
Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice.
Anesthesiology
Liu S,Mi WL,Li Q,Zhang MT,Han P,Hu S,Mao-Ying QL,Wang YQ
MA5-12023 was used in immunohistochemistry - frozen section and western blot to determine the correlation between neuronal caMKII-CREB and astroglial JAK2-STAT3 cascades in mice and how spinal IL-33/ST2 signaling contributes to neuropathic pain
Sun Nov 01 00:00:00 UTC 2015
Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres.
Stem cell research
Begum AN,Guoynes C,Cho J,Hao J,Lutfy K,Hong Y
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2015
Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres.
Stem cell research
Begum AN,Guoynes C,Cho J,Hao J,Lutfy K,Hong Y
Published figure using GFAP monoclonal antibody (Product # MA5-12023) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2015
Systemic and cerebral iron homeostasis in ferritin knock-out mice.
PloS one
Li W,Garringer HJ,Goodwin CB,Richine B,Acton A,VanDuyn N,Muhoberac BB,Irimia-Dominguez J,Chan RJ,Peacock M,Nass R,Ghetti B,Vidal R
MA5-12023 was used in immunohistochemistry - paraffin section to use Fth and Ftl knock out mice to study iron metabolism in the brain.
Thu Feb 04 00:00:00 UTC 2016
Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system.
Glia
Kitic M,Wimmer I,Adzemovic M,Kögl N,Rudel A,Lassmann H,Bradl M
MA5-12023 was used in immunohistochemistry to study the CNS expression of thymic stromal lymphopoietin and its upregulation under conditions of myelin degeneration
Tue Jul 01 00:00:00 UTC 2014
Multipotent adult hippocampal progenitor cells maintained as neurospheres favor differentiation toward glial lineages.
Biotechnology journal
Oh J,Daniels GJ,Chiou LS,Ye EA,Jeong YS,Sakaguchi DS
MA5-12023 was used in immunocytochemistry and immunohistochemistry to study the preference for glial differentiation of multipotent adult hippocampal progenitors cells cultured as free-floating cellular aggregates
Tue Jul 01 00:00:00 UTC 2014
Fractalkine signaling and Tau hyper-phosphorylation are associated with autophagic alterations in lentiviral Tau and Aβ1-42 gene transfer models.
Experimental neurology
Hebron ML,Algarzae NK,Lonskaya I,Moussa C
MA5-12023 was used in immunohistochemistry to study changes in autophagy and the roles of Tau hyperphosphorylation and fractalkine in an animal model of Abeta42-induced Tau hyperphosphorylation
Wed Jan 01 00:00:00 UTC 2014
TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.
Human molecular genetics
Yan S,Wang CE,Wei W,Gaertig MA,Lai L,Li S,Li XJ
MA5-12023 was used in immunocytochemistry, immunohistochemistry, and western blot to study the different pathological effects of mutant TDP-43 in murine neuronal and glial cells
Thu May 15 00:00:00 UTC 2014
Enhancement of Neural Stem Cells after Induction of Depression in Male Albino Rats (A histological & Immunohistochemical Study).
International journal of stem cells
Kamel Ismail ZM,Morcos MA,Eldin Mohammad MD,Gamal Aboulkhair A
MA5-12023 was used in immunohistochemistry - paraffin section to test if rhodiola rosea extract stimulates neuronal stem cell proliferation and improves depression
Sat Nov 01 00:00:00 UTC 2014
Electroacupuncture promotes proliferation of amplifying neural progenitors and preserves quiescent neural progenitors from apoptosis to alleviate depressive-like and anxiety-like behaviours.
Evidence-based complementary and alternative medicine : eCAM
Yang L,Yue N,Zhu X,Han Q,Li B,Liu Q,Wu G,Yu J
MA5-12023 was used in immunohistochemistry to study the beneficial effects of electroacupuncture in a rat model of depression and the role of proliferation of amplifying neural progenitors and inhibition of quiescent neural progenitor apoptosis
Thu Apr 10 00:00:00 UTC 2014
Development of a chemically extracted acellular muscle scaffold seeded with amniotic epithelial cells to promote spinal cord repair.
Journal of biomedical materials research. Part A
Xue H,Zhang XY,Liu JM,Song Y,Li YF,Chen D
MA5-12023 was used in immunohistochemistry to develop a novel acellular muscle scaffold containing amniotic epithelial cells for the repair of spinal cord injury
Tue Jan 01 00:00:00 UTC 2013
Cdh1 inhibits reactive astrocyte proliferation after oxygen-glucose deprivation and reperfusion.
Neurochemistry international
Qiu J,Zhang C,Lv Y,Zhang Y,Zhu C,Wang X,Yao W
MA5-12023 was used in immunocytochemistry to study the proliferation of reactive astrocytes following glucose/oxygen deprivation-reperfusion and the inhibitory effect of Cdh1
Thu Aug 01 00:00:00 UTC 2013
Changes in retinal aquaporin-9 (AQP9) expression in glaucoma.
Bioscience reports
Yang MH,Dibas A,Tyan YC
MA5-12023 was used in immunohistochemistry to investigate the expression of retinal aquaporin-9 in glaucoma
Tue Apr 23 00:00:00 UTC 2013
Involvement of the spinal NALP1 inflammasome in neuropathic pain and aspirin-triggered-15-epi-lipoxin A4 induced analgesia.
Neuroscience
Li Q,Tian Y,Wang ZF,Liu SB,Mi WL,Ma HJ,Wu GC,Wang J,Yu J,Wang YQ
MA5-12023 was used in immunohistochemistry to study the role of reduced NALP1 inflammasome activation in the analgesic effects of 15-epilipoxin A4 in a rat model of neuropathic pain
Thu Dec 19 00:00:00 UTC 2013
NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.
Brain research
Xue H,Zhang XY,Liu JM,Song Y,Liu TT,Chen D
MA5-12023 was used in immunohistochemistry to study the role of anti-inflammatory mechanisms in ability of nordihydroguaiaretic acid to protect against seconday damage in a rat model of spinal cord injury
Fri Jun 21 00:00:00 UTC 2013
Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation.
Yonsei medical journal
Choi YS,Jun IG,Kim SH,Park JY
MA5-12023 was used in immunohistochemistry to study the beneficial effects on mechanical allodynia and on the activation of microglia and astrocytes of intrathecal administration of lamotrigine in a rat model of neuropathic pain
Fri Mar 01 00:00:00 UTC 2013
Involvement of TREK-1 activity in astrocyte function and neuroprotection under simulated ischemia conditions.
Journal of molecular neuroscience : MN
Wu X,Liu Y,Chen X,Sun Q,Tang R,Wang W,Yu Z,Xie M
MA5-12023 was used in immunocytochemistry to study the role TREK-1 in the response of astrocytes to ischemia and the therapeutic significance
Fri Mar 01 00:00:00 UTC 2013
The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.
PloS one
Park YM,Lee WT,Bokara KK,Seo SK,Park SH,Kim JH,Yenari MA,Park KA,Lee JE
MA5-12023 was used in immunohistochemistry and western blot to study the roles of neuronal and glial BMP-2, -4 and -7 in the benefecial effects of agmatine on recovery from spinal cord injury in a murine model
Wed Jul 24 00:00:00 UTC 2013
T cell-activation in neuromyelitis optica lesions plays a role in their formation.
Acta neuropathologica communications
Pohl M,Kawakami N,Kitic M,Bauer J,Martins R,Fischer MT,Machado-Santos J,Mader S,Ellwart JW,Misu T,Fujihara K,Wekerle H,Reindl M,Lassmann H,Bradl M
MA5-12023 was used in immunohistochemistry to study the role of T-cell activation in the formation of neuromyelitis optica lesions
Tue Dec 24 00:00:00 UTC 2013
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury.
Brain : a journal of neurology
Fischer MT,Sharma R,Lim JL,Haider L,Frischer JM,Drexhage J,Mahad D,Bradl M,van Horssen J,Lassmann H
MA5-12023 was used in immunohistochemistry to study the role of NADPH oxidase in oxidative tissue damage and mitochondrial injury in active multiple sclerosis lesions
Thu Mar 01 00:00:00 UTC 2012
Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Shen W,Fruttiger M,Zhu L,Chung SH,Barnett NL,Kirk JK,Lee S,Coorey NJ,Killingsworth M,Sherman LS,Gillies MC
MA5-12023 was used in immunohistochemistry to study the neural and vascular pathologies resulting from the conditional ablation of Mller cells in a novel murine model
Wed Nov 07 00:00:00 UTC 2012
Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathway.
The journal of pain
Tan YH,Li K,Chen XY,Cao Y,Light AR,Fu KY
MA5-12023 was used in immunohistochemistry to study the role of spinal microglial Src and p38 MAPK in persistant pain in a formalin injection animal model
Mon Oct 01 00:00:00 UTC 2012
Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.
Human molecular genetics
Cho SH,Kim JY,Simons DL,Song JY,Le JH,Swindell EC,Jamrich M,Wu SM,Kim S
MA5-12023 was used in immunohistochemistry to develop a murine model of Leber congenital amaurosis by deleting retinal progenitor cell Pals1
Fri Jun 15 00:00:00 UTC 2012
Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid.
Journal of neuroscience research
Duran-Vilaregut J,Manich G,Del Valle J,Camins A,Pallàs M,Vilaplana J,Pelegrí C
MA5-12023 was used in immunohistochemistry to study the immunohistochemical expression of ATM, p53, Akt and GSK3-beta in a rat model of neurodegeneration
Sat Sep 01 00:00:00 UTC 2012
Differentiated adipose-derived stem cells promote myelination and enhance functional recovery in a rat model of chronic denervation.
Journal of neuroscience research
Tomita K,Madura T,Mantovani C,Terenghi G
MA5-12023 was used in immunohistochemistry to study the axon myelination and functional recovery promoted by differentiated adipose-derived stem cells in a chronically denervated rat model
Sun Jul 01 00:00:00 UTC 2012
The correlation between DTI parameters and levels of AQP-4 in the early phases of cerebral edema after hypoxic-ischemic/reperfusion injury in piglets.
Pediatric radiology
Wang H,Wang X,Guo Q
MA5-12023 was used in immunohistochemistry to use a porcine model of hypoxic ischemia-reperfusion injury to study the relationship between diffusion tenser imaging parameters and aquaporin-4 expression in early-stage cerebral edema
Wed Aug 01 00:00:00 UTC 2012
Changes in lipid-sensitive two-pore domain potassium channel TREK-1 expression and its involvement in astrogliosis following cerebral ischemia in rats.
Journal of molecular neuroscience : MN
Wang M,Song J,Xiao W,Yang L,Yuan J,Wang W,Yu Z,Xie M
MA5-12023 was used in immunocytochemistry and immunohistochemistry to study the effects of cerebral ischemia on the expression of TREK-1 and the significance for astrogliosis
Wed Feb 01 00:00:00 UTC 2012
Multiple endocardial neurofibromas in a rosy-billed pochard (Netta peposaca).
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Miller AD,Baitchman EJ,Masek-Hammerman K
MA5-12023 was used in immunohistochemistry to report on a case of a rosy-billed pochard with multiple endocardial neurofibromas
Thu Mar 01 00:00:00 UTC 2012
Adsorption of mesenchymal stem cells and cortical neural stem cells on carbon nanotube/polycarbonate urethane.
Nanomedicine (London, England)
Nho Y,Kim JY,Khang D,Webster TJ,Lee JE
MA5-12023 was used in immunocytochemistry to study the effect of carbon nanotubes on stem cell survival
Thu Apr 01 00:00:00 UTC 2010
CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery.
Brain : a journal of neurology
Schwab N,Bien CG,Waschbisch A,Becker A,Vince GH,Dornmair K,Wiendl H
MA5-12023 was used in immunohistochemistry to examine the involvement of CD8+ T cells in the pathogenesis of Rasmussen encephalitis
Fri May 01 00:00:00 UTC 2009
Embryonic porcine liver as a source for transplantation: advantage of intact liver implants over isolated hepatoblasts in overcoming homeostatic inhibition by the quiescent host liver.
Stem cells (Dayton, Ohio)
Katchman H,Tal O,Eventov-Friedman S,Shezen E,Aronovich A,Tchorsh D,Cohen S,Shtabsky A,Hecht G,Dekel B,Freud E,Reisner Y
MA5-12023 was used in immunohistochemistry to study ether xenotransplantation of pig fetal liver fragments can provide better growth and proliferation compared with isolated pig fetal hepatoblasts
Thu May 01 00:00:00 UTC 2008
