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          • Primary Antibodies ›
          • GFM2 Antibodies

          Invitrogen

          GFM2 Polyclonal Antibody

          View all (8) GFM2 antibodies

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          Cite GFM2 Polyclonal Antibody

          • Antibody Testing Data (2)
          GFM2 Antibody in Western Blot (WB)
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          GFM2 Antibody in Western Blot (WB)
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          FIGURE: 1 / 2

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          GFM2 Antibody (PA5-85482) in WB

          Western blot analysis of GFM2 in various whole cell extracts (30 μg). Samples were incubated with GFM2 polyclonal antibody (Product # PA5-85482) using a dilution of 1:2,000. Separated by 7.5% SDS-PAGE. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GFM2 Antibody in Western Blot (WB)
          GFM2 Antibody in Western Blot (WB)

          Product Details

          PA5-85482

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human GFM2. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 20% glycerol

          Contains

          0.025% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Wet ice

          RRID

          AB_2792622

          Product Specific Information

          Keep as concentrated solution.

          Predicted reactivity: Mouse (88%), Rat (87%), Rhesus Monkey (98%), Bovine (91%).

          Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, C8D30.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: EF-G2mt; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor; G elongation factor, mitochondrial 2; GFM2; hEFG2; mEF-G 2; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2mt

          View more View less

          Gene Aliases: 6530419G12Rik; A930009M04Rik; EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt

          View more View less

          UniProt ID: (Human) Q969S9, (Mouse) Q8R2Q4

          View more View less

          Entrez Gene ID: (Human) 84340, (Mouse) 320806

          View more View less

          Function(s)
          translation elongation factor activity GTPase activity protein binding GTP binding nucleotide binding
          Process(es)
          translation mitochondrial translation ribosome disassembly mitochondrial translational elongation mitochondrial translational termination
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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