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Antibody detects endogenous levels of total GFRA4.
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Protein Aliases: GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR receptor alpha 4; GFR-alpha-4; Persephin receptor
Gene Aliases: GFRA4
UniProt ID: (Human) Q9GZZ7
Entrez Gene ID: (Human) 64096
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