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The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Protein Aliases: GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha-4; GFR receptor alpha 4; GFR-alpha-4; glial cell line derived neurotrophic factor family receptor alpha 4; neurotrophic factor receptor splice variant A (Gfra4 gene); Persephin receptor
Gene Aliases: AW060733; G630015H18Rik; GFRA4
UniProt ID: (Human) Q9GZZ7, (Rat) Q9EPI2, (Mouse) Q9JJT2
Entrez Gene ID: (Human) 64096, (Rat) 66023, (Mouse) 14588
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